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The First Two Liver Transplantations in Syria

Liver transplantation (LT) is the only curative therapy for the end-stage liver diseases and some metabolic disorders which affect the hepatic cell like the Crigler-Najjar syndrome type 1 (CNSI). Although the LT is a routine procedure in many centers worldwide, the postoperative complications such a...

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Autor principal: Rayya, Fadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989781/
https://www.ncbi.nlm.nih.gov/pubmed/33790718
http://dx.doi.org/10.1159/000513281
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author Rayya, Fadi
author_facet Rayya, Fadi
author_sort Rayya, Fadi
collection PubMed
description Liver transplantation (LT) is the only curative therapy for the end-stage liver diseases and some metabolic disorders which affect the hepatic cell like the Crigler-Najjar syndrome type 1 (CNSI). Although the LT is a routine procedure in many centers worldwide, the postoperative complications such as rejection, arterial thrombosis, and infection remain serious challenges even in big centers. In our paper, we demonstrate the first two LTs in Syria. The first one was performed on 6 February 2016 for an 11-year-old boy suffering from CNSI using an auxiliary LT, but unfortunately, he had a hepatic artery and portal vein thrombosis, so we removed the necrotic graft on the fifth postoperative day, and he survived. The second LT was for a 9-year-old boy, who had cryptogenic liver cirrhosis, and he lived for 31 days after the transplantation. In both transplants, grafts were obtained from living relative donors.
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spelling pubmed-79897812021-03-30 The First Two Liver Transplantations in Syria Rayya, Fadi Case Rep Gastroenterol Case Series Liver transplantation (LT) is the only curative therapy for the end-stage liver diseases and some metabolic disorders which affect the hepatic cell like the Crigler-Najjar syndrome type 1 (CNSI). Although the LT is a routine procedure in many centers worldwide, the postoperative complications such as rejection, arterial thrombosis, and infection remain serious challenges even in big centers. In our paper, we demonstrate the first two LTs in Syria. The first one was performed on 6 February 2016 for an 11-year-old boy suffering from CNSI using an auxiliary LT, but unfortunately, he had a hepatic artery and portal vein thrombosis, so we removed the necrotic graft on the fifth postoperative day, and he survived. The second LT was for a 9-year-old boy, who had cryptogenic liver cirrhosis, and he lived for 31 days after the transplantation. In both transplants, grafts were obtained from living relative donors. S. Karger AG 2021-03-11 /pmc/articles/PMC7989781/ /pubmed/33790718 http://dx.doi.org/10.1159/000513281 Text en Copyright © 2021 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Series
Rayya, Fadi
The First Two Liver Transplantations in Syria
title The First Two Liver Transplantations in Syria
title_full The First Two Liver Transplantations in Syria
title_fullStr The First Two Liver Transplantations in Syria
title_full_unstemmed The First Two Liver Transplantations in Syria
title_short The First Two Liver Transplantations in Syria
title_sort first two liver transplantations in syria
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989781/
https://www.ncbi.nlm.nih.gov/pubmed/33790718
http://dx.doi.org/10.1159/000513281
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