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A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor
Gastric mixed adenocarcinoma-neuroendocrine tumor (NET) is a rare composite tumor, and a limited number of studies have reported on it. A 77-year-old man was admitted to our hospital because of acute cholecystitis. He underwent a cholecystectomy. Esophagogastroduodenoscopy during his admission revea...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989826/ https://www.ncbi.nlm.nih.gov/pubmed/33790721 http://dx.doi.org/10.1159/000513802 |
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author | Sano, Yoshifumi Saito, Shoichi Kawachi, Hiroshi Tsutsumi, Jun Fujisaki, Junko |
author_facet | Sano, Yoshifumi Saito, Shoichi Kawachi, Hiroshi Tsutsumi, Jun Fujisaki, Junko |
author_sort | Sano, Yoshifumi |
collection | PubMed |
description | Gastric mixed adenocarcinoma-neuroendocrine tumor (NET) is a rare composite tumor, and a limited number of studies have reported on it. A 77-year-old man was admitted to our hospital because of acute cholecystitis. He underwent a cholecystectomy. Esophagogastroduodenoscopy during his admission revealed a slightly elevated tumor, and biopsy demonstrated a well-differentiated tubular adenocarcinoma. The tumor was resected completely by endoscopic submucosal dissection. Histological findings showed that it measured 9 mm in diameter, was located within the mucosa, and consisted of well-differentiated tubular adenocarcinoma and a NET G1. The NET was covered with adenocarcinoma and both components exhibited histological continuity. The NET and a part of the adenocarcinoma component showed a positive reaction for chromogranin A and synaptophysin. Neither enterochromaffin-like cell hyperplasia nor endocrine cell micronest surrounded the tumor. The diagnosis was gastric mixed adenocarcinoma-NET. The histological continuity between the two components can be likened to the same histogenesis. |
format | Online Article Text |
id | pubmed-7989826 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-79898262021-03-30 A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor Sano, Yoshifumi Saito, Shoichi Kawachi, Hiroshi Tsutsumi, Jun Fujisaki, Junko Case Rep Gastroenterol Single Case Gastric mixed adenocarcinoma-neuroendocrine tumor (NET) is a rare composite tumor, and a limited number of studies have reported on it. A 77-year-old man was admitted to our hospital because of acute cholecystitis. He underwent a cholecystectomy. Esophagogastroduodenoscopy during his admission revealed a slightly elevated tumor, and biopsy demonstrated a well-differentiated tubular adenocarcinoma. The tumor was resected completely by endoscopic submucosal dissection. Histological findings showed that it measured 9 mm in diameter, was located within the mucosa, and consisted of well-differentiated tubular adenocarcinoma and a NET G1. The NET was covered with adenocarcinoma and both components exhibited histological continuity. The NET and a part of the adenocarcinoma component showed a positive reaction for chromogranin A and synaptophysin. Neither enterochromaffin-like cell hyperplasia nor endocrine cell micronest surrounded the tumor. The diagnosis was gastric mixed adenocarcinoma-NET. The histological continuity between the two components can be likened to the same histogenesis. S. Karger AG 2021-03-11 /pmc/articles/PMC7989826/ /pubmed/33790721 http://dx.doi.org/10.1159/000513802 Text en Copyright © 2021 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Single Case Sano, Yoshifumi Saito, Shoichi Kawachi, Hiroshi Tsutsumi, Jun Fujisaki, Junko A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor |
title | A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor |
title_full | A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor |
title_fullStr | A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor |
title_full_unstemmed | A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor |
title_short | A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor |
title_sort | gastric intramucosal mixed adenocarcinoma-neuroendocrine tumor |
topic | Single Case |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989826/ https://www.ncbi.nlm.nih.gov/pubmed/33790721 http://dx.doi.org/10.1159/000513802 |
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