A freeze-and-thaw-induced fragment of the microtubule-associated protein tau in rat brain extracts: implications for the biochemical assessment of neurotoxicity

Tau is a microtubule-associated protein (MAP) responsible for controlling the stabilization of microtubules in neurons. Tau function is regulated by phosphorylation. However, in some neurological diseases Tau becomes aberrantly hyperphosphorylated, which contributes to the pathogenesis of neurologic...

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Detalles Bibliográficos
Autores principales: Vasconcelos, Israel C., Campos, Raquel M., Schwaemmle, Hanna K., Masson, Ana P., Ferrari, Gustavo D., Alberici, Luciane C., Faça, Vitor M., Garcia-Cairasco, Norberto, Sebollela, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Molecular Bases of Health & Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990086/
https://www.ncbi.nlm.nih.gov/pubmed/33629708
http://dx.doi.org/10.1042/BSR20203980

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