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Neuronal death in pneumococcal meningitis is triggered by pneumolysin and RrgA interactions with β-actin
Neuronal damage is a major consequence of bacterial meningitis, but little is known about mechanisms of bacterial interaction with neurons leading to neuronal cell death. Streptococcus pneumoniae (pneumococcus) is a leading cause of bacterial meningitis and many survivors develop neurological sequel...
Autores principales: | Tabusi, Mahebali, Thorsdottir, Sigrun, Lysandrou, Maria, Narciso, Ana Rita, Minoia, Melania, Srambickal, Chinmaya Venugopal, Widengren, Jerker, Henriques-Normark, Birgitta, Iovino, Federico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990213/ https://www.ncbi.nlm.nih.gov/pubmed/33760879 http://dx.doi.org/10.1371/journal.ppat.1009432 |
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