A blocking antibody against canine CSF-1R maturated by limited CDR mutagenesis

CSF-1R is a receptor mostly associated with the mononuclear phagocytic system. However, its expression within tumors has been linked with poor prognosis in both humans and dogs. Accordingly, several reports have demonstrated the beneficial effects of blocking CSF-1R in model systems of cancer. In th...

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Detalles Bibliográficos
Autores principales: Beirão, Breno C B, Raposo, Teresa P, Imamura, Louise M, Ingberman, Max, Hupp, Ted, Vojtěšek, Bořivoj, Argyle, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990251/
https://www.ncbi.nlm.nih.gov/pubmed/33937625
http://dx.doi.org/10.1093/abt/tbaa018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990251/
https://www.ncbi.nlm.nih.gov/pubmed/33937625
http://dx.doi.org/10.1093/abt/tbaa018

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