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Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen

Virus host shifts are generally associated with novel adaptations to exploit the cells of the new host species optimally. Surprisingly, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has apparently required little to no significant adaptation to humans since the start of the Coronaviru...

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Detalles Bibliográficos
Autores principales: MacLean, Oscar A., Lytras, Spyros, Weaver, Steven, Singer, Joshua B., Boni, Maciej F., Lemey, Philippe, Kosakovsky Pond, Sergei L., Robertson, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990310/
https://www.ncbi.nlm.nih.gov/pubmed/33711012
http://dx.doi.org/10.1371/journal.pbio.3001115

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