Catalytic photooxygenation degrades brain Aβ in vivo

Protein degradation induced by small molecules by recruiting endogenous protein degradation systems, such as ubiquitin-proteasome systems, to disease-related proteins is an emerging concept to inhibit the function of undruggable proteins. Protein targets without reliable ligands and/or existing outs...

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Detalles Bibliográficos
Autores principales: Nagashima, Nozomu, Ozawa, Shuta, Furuta, Masahiro, Oi, Miku, Hori, Yukiko, Tomita, Taisuke, Sohma, Youhei, Kanai, Motomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990327/
https://www.ncbi.nlm.nih.gov/pubmed/33762329
http://dx.doi.org/10.1126/sciadv.abc9750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990327/
https://www.ncbi.nlm.nih.gov/pubmed/33762329
http://dx.doi.org/10.1126/sciadv.abc9750

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