Ca(2+) signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG

Calcium signaling regulated by the cGMP-dependent protein kinase (PKG) controls key life cycle transitions in the malaria parasite. However, how calcium is mobilized from intracellular stores in the absence of canonical calcium channels in Plasmodium is unknown. Here, we identify a multipass membran...

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Detalles Bibliográficos
Autores principales: Balestra, Aurélia C., Koussis, Konstantinos, Klages, Natacha, Howell, Steven A., Flynn, Helen R., Bantscheff, Marcus, Pasquarello, Carla, Perrin, Abigail J., Brusini, Lorenzo, Arboit, Patrizia, Sanz, Olalla, Castaño, Laura Peces-Barba, Withers-Martinez, Chrislaine, Hainard, Alexandre, Ghidelli-Disse, Sonja, Snijders, Ambrosius P., Baker, David A., Blackman, Michael J., Brochet, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990342/
https://www.ncbi.nlm.nih.gov/pubmed/33762339
http://dx.doi.org/10.1126/sciadv.abe5396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990342/
https://www.ncbi.nlm.nih.gov/pubmed/33762339
http://dx.doi.org/10.1126/sciadv.abe5396

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