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SARS-CoV-2 Emergency and Long-Term Cognitive Impairment in Older People

The SARS-CoV-2 infection has spread to all continents, affecting particularly older people. The complexity of SARS-CoV2 infection is still under study. Despite respiratory involvement is the main clinical manifestation of COVID-19, neurological manifestations are common. Although it is obvious to gi...

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Detalles Bibliográficos
Autores principales: Rizzo, Maria Rosaria, Paolisso, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990368/
https://www.ncbi.nlm.nih.gov/pubmed/33815868
http://dx.doi.org/10.14336/AD.2021.0109
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author Rizzo, Maria Rosaria
Paolisso, Giuseppe
author_facet Rizzo, Maria Rosaria
Paolisso, Giuseppe
author_sort Rizzo, Maria Rosaria
collection PubMed
description The SARS-CoV-2 infection has spread to all continents, affecting particularly older people. The complexity of SARS-CoV2 infection is still under study. Despite respiratory involvement is the main clinical manifestation of COVID-19, neurological manifestations are common. Although it is obvious to give priority to infectious emergency and the infectious disease itself, at present, however, data on potential long-term damages generally and on long-term cognitive functions impairment of older COVID-19 survivors have yet to be investigated. Because the hypothesis on the involvement of SARS-CoV-2 on the long-term cognitive decline pathogenesis would seem difficult to prove, we wanted to explore the brain mechanisms of SARS-CoV-2, in order to provide more in-depth analysis and to draw attention to a topic relevant to basic scientific research and, more generally, to the elderly population.Looking forward, we argue that an early clinical and instrumental cognitive assessment can help prevent and slow down this possible complication or at least improve the quality of life for older people Covid-19 survivor.
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spelling pubmed-79903682021-04-03 SARS-CoV-2 Emergency and Long-Term Cognitive Impairment in Older People Rizzo, Maria Rosaria Paolisso, Giuseppe Aging Dis Opinion The SARS-CoV-2 infection has spread to all continents, affecting particularly older people. The complexity of SARS-CoV2 infection is still under study. Despite respiratory involvement is the main clinical manifestation of COVID-19, neurological manifestations are common. Although it is obvious to give priority to infectious emergency and the infectious disease itself, at present, however, data on potential long-term damages generally and on long-term cognitive functions impairment of older COVID-19 survivors have yet to be investigated. Because the hypothesis on the involvement of SARS-CoV-2 on the long-term cognitive decline pathogenesis would seem difficult to prove, we wanted to explore the brain mechanisms of SARS-CoV-2, in order to provide more in-depth analysis and to draw attention to a topic relevant to basic scientific research and, more generally, to the elderly population.Looking forward, we argue that an early clinical and instrumental cognitive assessment can help prevent and slow down this possible complication or at least improve the quality of life for older people Covid-19 survivor. JKL International LLC 2021-04-01 /pmc/articles/PMC7990368/ /pubmed/33815868 http://dx.doi.org/10.14336/AD.2021.0109 Text en copyright: © 2021 Rizzo et al. http://creativecommons.org/licenses/by/2.0/ this is an open access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Opinion
Rizzo, Maria Rosaria
Paolisso, Giuseppe
SARS-CoV-2 Emergency and Long-Term Cognitive Impairment in Older People
title SARS-CoV-2 Emergency and Long-Term Cognitive Impairment in Older People
title_full SARS-CoV-2 Emergency and Long-Term Cognitive Impairment in Older People
title_fullStr SARS-CoV-2 Emergency and Long-Term Cognitive Impairment in Older People
title_full_unstemmed SARS-CoV-2 Emergency and Long-Term Cognitive Impairment in Older People
title_short SARS-CoV-2 Emergency and Long-Term Cognitive Impairment in Older People
title_sort sars-cov-2 emergency and long-term cognitive impairment in older people
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990368/
https://www.ncbi.nlm.nih.gov/pubmed/33815868
http://dx.doi.org/10.14336/AD.2021.0109
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