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The Contribution of Somatic Expansion of the CAG Repeat to Symptomatic Development in Huntington’s Disease: A Historical Perspective
The discovery in the early 1990s of the expansion of unstable simple sequence repeats as the causative mutation for a number of inherited human disorders, including Huntington’s disease (HD), opened up a new era of human genetics and provided explanations for some old problems. In particular, an inv...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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IOS Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990401/ https://www.ncbi.nlm.nih.gov/pubmed/33579863 http://dx.doi.org/10.3233/JHD-200429 |