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Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer’s Disease

We explored the impact of the Spanish COVID-19 strict home confinement on mental health and cognition in non-infected subjects (N = 16, 60–80 years) diagnosed with subjective cognitive decline and APOE ɛ3/ɛ4 carriers. Mental health was monitored for 2 months on a daily, weekly, or monthly basis, and...

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Autores principales: Soldevila-Domenech, Natalia, Forcano, Laura, Boronat, Anna, Lorenzo, Thais, Piera, Iris, Puig-Pijoan, Albert, Mateus, Julian, González de Echevarri Gómez, José María, Knezevic, Iva, Soteras, Anna, Fauria, Karine, Pizarro, Nieves, Molinuevo, Jose Luis, de la Torre, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990405/
https://www.ncbi.nlm.nih.gov/pubmed/33386809
http://dx.doi.org/10.3233/JAD-201408
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author Soldevila-Domenech, Natalia
Forcano, Laura
Boronat, Anna
Lorenzo, Thais
Piera, Iris
Puig-Pijoan, Albert
Mateus, Julian
González de Echevarri Gómez, José María
Knezevic, Iva
Soteras, Anna
Fauria, Karine
Pizarro, Nieves
Molinuevo, Jose Luis
de la Torre, Rafael
author_facet Soldevila-Domenech, Natalia
Forcano, Laura
Boronat, Anna
Lorenzo, Thais
Piera, Iris
Puig-Pijoan, Albert
Mateus, Julian
González de Echevarri Gómez, José María
Knezevic, Iva
Soteras, Anna
Fauria, Karine
Pizarro, Nieves
Molinuevo, Jose Luis
de la Torre, Rafael
author_sort Soldevila-Domenech, Natalia
collection PubMed
description We explored the impact of the Spanish COVID-19 strict home confinement on mental health and cognition in non-infected subjects (N = 16, 60–80 years) diagnosed with subjective cognitive decline and APOE ɛ3/ɛ4 carriers. Mental health was monitored for 2 months on a daily, weekly, or monthly basis, and compared to pre-confinement values. Emotional distress, anxiety, and depression scores increased to pathological threshold values during and after confinement. Those with lower mood during confinement experienced a decline in their mood after confinement. Cognition did not change. These preliminary results suggest that mental health consequences of corona measures in preclinical stages of Alzheimer’s disease should be further evaluated.
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spelling pubmed-79904052021-04-14 Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer’s Disease Soldevila-Domenech, Natalia Forcano, Laura Boronat, Anna Lorenzo, Thais Piera, Iris Puig-Pijoan, Albert Mateus, Julian González de Echevarri Gómez, José María Knezevic, Iva Soteras, Anna Fauria, Karine Pizarro, Nieves Molinuevo, Jose Luis de la Torre, Rafael J Alzheimers Dis Short Communication We explored the impact of the Spanish COVID-19 strict home confinement on mental health and cognition in non-infected subjects (N = 16, 60–80 years) diagnosed with subjective cognitive decline and APOE ɛ3/ɛ4 carriers. Mental health was monitored for 2 months on a daily, weekly, or monthly basis, and compared to pre-confinement values. Emotional distress, anxiety, and depression scores increased to pathological threshold values during and after confinement. Those with lower mood during confinement experienced a decline in their mood after confinement. Cognition did not change. These preliminary results suggest that mental health consequences of corona measures in preclinical stages of Alzheimer’s disease should be further evaluated. IOS Press 2021-02-02 /pmc/articles/PMC7990405/ /pubmed/33386809 http://dx.doi.org/10.3233/JAD-201408 Text en © 2021 – The authors. Published by IOS Press https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Soldevila-Domenech, Natalia
Forcano, Laura
Boronat, Anna
Lorenzo, Thais
Piera, Iris
Puig-Pijoan, Albert
Mateus, Julian
González de Echevarri Gómez, José María
Knezevic, Iva
Soteras, Anna
Fauria, Karine
Pizarro, Nieves
Molinuevo, Jose Luis
de la Torre, Rafael
Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer’s Disease
title Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer’s Disease
title_full Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer’s Disease
title_fullStr Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer’s Disease
title_full_unstemmed Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer’s Disease
title_short Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer’s Disease
title_sort effects of covid-19 home confinement on mental health in individuals with increased risk of alzheimer’s disease
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990405/
https://www.ncbi.nlm.nih.gov/pubmed/33386809
http://dx.doi.org/10.3233/JAD-201408
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