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DNA Mismatch Repair and its Role in Huntington’s Disease

DNA mismatch repair (MMR) is a highly conserved genome stabilizing pathway that corrects DNA replication errors, limits chromosomal rearrangements, and mediates the cellular response to many types of DNA damage. Counterintuitively, MMR is also involved in the generation of mutations, as evidenced by...

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Detalles Bibliográficos
Autores principales: Iyer, Ravi R., Pluciennik, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990411/
https://www.ncbi.nlm.nih.gov/pubmed/33579865
http://dx.doi.org/10.3233/JHD-200438

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