Cargando…

Overexpression of HSP10 correlates with HSP60 and Mcl-1 levels and predicts poor prognosis in non-small cell lung cancer patients

BACKGROUND: HSP60 and its partner HSP10 are members of heat shock proteins (HSPs) family, which help mitochondrial protein to fold correctly. Mcl-1, a member of the Bcl-2 family, plays a crucial role in regulation of cell apoptosis. Aberrant expression of HSP10, HSP60 and Mcl-1 is involved in the de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Yaoxiang, Yang, Yang, Luo, Jiadi, Liu, Sile, Zhan, Yuting, Zang, Hongjing, Zheng, Hongmei, Zhang, Yuting, Feng, Juan, Fan, Songqing, Wen, Qiuyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990427/ https://www.ncbi.nlm.nih.gov/pubmed/32986659 http://dx.doi.org/10.3233/CBM-200410

Ejemplares similares

High expression of HSP60 and survivin predicts poor prognosis for oral squamous cell carcinoma patients
por: Zhou, Ying, et al.
Publicado: (2023)

Overexpression of p-4EBP1 associates with p-eIF4E and predicts poor prognosis for non-small cell lung cancer patients with resection
por: Tang, Yaoxiang, et al.
Publicado: (2022)

Overexpressed p-S6 associates with lymph node metastasis and predicts poor prognosis in non-small cell lung cancer
por: Tang, Yaoxiang, et al.
Publicado: (2022)

Increased expression of heat shock protein (HSP) 10 and HSP70 correlates with poor prognosis of nasopharyngeal carcinoma
por: Feng, Juan, et al.
Publicado: (2019)

Elevated expression of mcl-1 inhibits apoptosis and predicts poor prognosis in patients with surgically resected non-small cell lung cancer
por: Wen, Qiuyuan, et al.
Publicado: (2019)

Overexpression of P4HA1 associates with poor prognosis and promotes cell proliferation and metastasis of lung adenocarcinoma
por: Ning, Yue, et al.
Publicado: (2021)

Overexpression of p-Akt, p-mTOR and p-eIF4E proteins associates with metastasis and unfavorable prognosis in non-small cell lung cancer
por: Lu, Junmi, et al.
Publicado: (2020)

Comprehensive analysis of the mechanism and treatment significance of Mucins in lung cancer
por: Ning, Yue, et al.
Publicado: (2020)

Elevated expression of HSP10 protein inhibits apoptosis and associates with poor prognosis of astrocytoma
por: Fan, Weibing, et al.
Publicado: (2017)

Elevated expression of G3BP1 associates with YB1 and p‐AKT and predicts poor prognosis in nonsmall cell lung cancer patients after surgical resection
por: Zheng, Hongmei, et al.
Publicado: (2019)

Co-expression of PD-L1 and HIF-1α predicts poor prognosis in Patients with Non-small Cell Lung Cancer after surgery
por: Zheng, Hongmei, et al.
Publicado: (2021)

miR-4634 augments the anti-tumor effects of RAD001 and associates well with clinical prognosis of non-small cell lung cancer
por: Liu, Sile, et al.
Publicado: (2020)

Exosome-mediated miR-7-5p delivery enhances the anticancer effect of Everolimus via blocking MNK/eIF4E axis in non-small cell lung cancer
por: Liu, Sile, et al.
Publicado: (2022)

Expression of WDR79 is associated with TP53 mutation and poor prognosis in surgically resected non-small cell lung cancer
por: Peng, Jinwu, et al.
Publicado: (2019)

YB1 associates with oncogenetic roles and poor prognosis in nasopharyngeal carcinoma
por: Zhan, Yuting, et al.
Publicado: (2022)

AXL in cancer: a modulator of drug resistance and therapeutic target
por: Tang, Yaoxiang, et al.
Publicado: (2023)

Increased expression of FAT4 suppress metastasis of lung adenocarcinoma through regulating MAPK pathway and associated with immune cells infiltration
por: Ning, Yue, et al.
Publicado: (2022)

YAP1 synergize with YY1 transcriptional co-repress DUSP1 to induce osimertinib resistant by activating the EGFR/MAPK pathway and abrogating autophagy in non-small cell lung cancer
por: Ning, Yue, et al.
Publicado: (2023)

Expression of DR5 and c-FLIP proteins as novel prognostic biomarkers for non-small cell lung cancer patients treated with surgical resection and chemotherapy
por: Zheng, Hongmei, et al.
Publicado: (2019)

New insights into the important roles of tumor cell-intrinsic PD-1
por: Zheng, Hongmei, et al.
Publicado: (2021)

The expression of HSP60 and HSP10 in large bowel carcinomas with lymph node metastase
por: Cappello, Francesco, et al.
Publicado: (2005)

HSP60 possesses a GTPase activity and mediates protein folding with HSP10
por: Okamoto, Tomoya, et al.
Publicado: (2017)

Role of HSP60/HSP10 in Lung Cancer: Simple Biomarkers or Leading Actors?
por: Fucarino, Alberto, et al.
Publicado: (2020)

Molecular characterization of the Corynebacterium pseudotuberculosis hsp60-hsp10 operon, and evaluation of the immune response and protective efficacy induced by hsp60 DNA vaccination in mice
por: Costa, Marcilia P, et al.
Publicado: (2011)

The roles of tumor-derived exosomes in non-small cell lung cancer and their clinical implications
por: Zheng, Hongmei, et al.
Publicado: (2018)

Prognostic analysis of patients with mutant and wild-type EGFR gene lung adenocarcinoma
por: Zheng, Hongmei, et al.
Publicado: (2019)

Developmental Expression of HSP60 and HSP10 in the Coilia nasus Testis during Upstream Spawning Migration
por: Fang, Di-An, et al.
Publicado: (2017)

Aberrant Expression of β-Catenin Correlates with Infiltrating Immune Cells and Prognosis in NSCLC
por: Zheng, Hongmei, et al.
Publicado: (2021)

Different Immunohistochemical Levels of Hsp60 and Hsp70 in a Subset of Brain Tumors and Putative Role of Hsp60 in Neuroepithelial Tumorigenesis
por: Rappa, F., et al.
Publicado: (2013)

Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin
por: Gomez-Llorente, Yacob, et al.
Publicado: (2020)

The Chaperone System in Breast Cancer: Roles and Therapeutic Prospects of the Molecular Chaperones Hsp27, Hsp60, Hsp70, and Hsp90
por: Alberti, Giusi, et al.
Publicado: (2022)

Expression of cancer cell-intrinsic PD-1 associates with PD-L1 and p-S6 and predicts a good prognosis in nasopharyngeal carcinoma
por: Zhang, Yuting, et al.
Publicado: (2021)

Antibodies against Hsp60 and Hsp65 in the sera of women with ovarian cancer
por: Bodzek, Piotr, et al.
Publicado: (2014)

High expression of HSP90 is associated with poor prognosis in patients with colorectal cancer
por: Zhang, Shuming, et al.
Publicado: (2019)

Whey Protein Hydrolysate Enhances HSP90 but Does Not Alter HSP60 and HSP25 in Skeletal Muscle of Rats
por: Moura, Carolina Soares, et al.
Publicado: (2014)

Mitochondrial HSP70, HSP40, and HSP60 bind to the 3′ untranslated region of the Murine hepatitis virus genome
por: Nanda, S. K., et al.
Publicado: (2003)

HSP60 Regulates Lipid Metabolism in Human Ovarian Cancer
por: Li, Na, et al.
Publicado: (2021)

Genome-wide identification and expression analysis of the Hsp20, Hsp70 and Hsp90 gene family in Dendrobium officinale
por: Wang, Hongman, et al.
Publicado: (2022)

Resistance to HSP90 inhibition involving loss of MCL1 addiction
por: Busacca, S, et al.
Publicado: (2016)

Disease-Associated Mutations in the HSPD1 Gene Encoding the Large Subunit of the Mitochondrial HSP60/HSP10 Chaperonin Complex
por: Bross, Peter, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_466q8ouhcc1sn0540vne4ri19p