Modifiers of Somatic Repeat Instability in Mouse Models of Friedreich Ataxia and the Fragile X-Related Disorders: Implications for the Mechanism of Somatic Expansion in Huntington’s Disease

Huntington’s disease (HD) is one of a large group of human disorders that are caused by expanded DNA repeats. These repeat expansion disorders can have repeat units of different size and sequence that can be located in any part of the gene and, while the pathological consequences of the expansion ca...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaonan, Kumari, Daman, Miller, Carson J., Kim, Geum-Yi, Hayward, Bruce, Vitalo, Antonia G., Pinto, Ricardo Mouro, Usdin, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990428/
https://www.ncbi.nlm.nih.gov/pubmed/33579860
http://dx.doi.org/10.3233/JHD-200423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990428/
https://www.ncbi.nlm.nih.gov/pubmed/33579860
http://dx.doi.org/10.3233/JHD-200423

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