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Drugging DNA Damage Repair Pathways for Trinucleotide Repeat Expansion Diseases

DNA damage repair (DDR) mechanisms have been implicated in a number of neurodegenerative diseases (both genetically determined and sporadic). Consistent with this, recent genome-wide association studies in Huntington’s disease (HD) and other trinucleotide repeat expansion diseases have highlighted g...

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Detalles Bibliográficos
Autores principales:	Benn, Caroline L., Gibson, Karl R., Reynolds, David S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990437/ https://www.ncbi.nlm.nih.gov/pubmed/32925081 http://dx.doi.org/10.3233/JHD-200421

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