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COVID-19 Vaccination for Persons with Parkinson’s Disease: Light at the End of the Tunnel?

Several COVID-19 vaccines have recently been approved for emergency use according to governmental immunization programs. The arrival of these vaccines has created hope for people with Parkinson’s disease (PD), as this can help to mitigate their risk of becoming infected with the severe acute respira...

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Autores principales: Bloem, Bastiaan R., Trenkwalder, Claudia, Sanchez-Ferro, Alvaro, Kalia, Lorraine V., Alcalay, Roy, Chiang, Han-Lin, Kang, Un Jung, Goetz, Christopher, Brundin, Patrik, Papa, Stella M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990445/
https://www.ncbi.nlm.nih.gov/pubmed/33523021
http://dx.doi.org/10.3233/JPD-212573
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author Bloem, Bastiaan R.
Trenkwalder, Claudia
Sanchez-Ferro, Alvaro
Kalia, Lorraine V.
Alcalay, Roy
Chiang, Han-Lin
Kang, Un Jung
Goetz, Christopher
Brundin, Patrik
Papa, Stella M.
author_facet Bloem, Bastiaan R.
Trenkwalder, Claudia
Sanchez-Ferro, Alvaro
Kalia, Lorraine V.
Alcalay, Roy
Chiang, Han-Lin
Kang, Un Jung
Goetz, Christopher
Brundin, Patrik
Papa, Stella M.
author_sort Bloem, Bastiaan R.
collection PubMed
description Several COVID-19 vaccines have recently been approved for emergency use according to governmental immunization programs. The arrival of these vaccines has created hope for people with Parkinson’s disease (PD), as this can help to mitigate their risk of becoming infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can lead to serious, life-threatening disease, at least among those with more advanced PD. However, both persons with PD and physicians looking after these individuals have expressed concerns about the vaccine’s efficacy and safety in the specific context of PD and its symptomatic treatment. Here, we discuss our perspective on these concerns, based on our interpretation of the literature plus the unfolding experience with widespread vaccination in the population at large. Because the benefits and risks of COVID-19 vaccines do not appear to be different than in the general population, we recommend COVID-19 vaccination with approved vaccines to persons with PD, unless there is a specific contraindication. Some caution seems warranted in very frail and terminally ill elderly persons with PD living in long-term care facilities.
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spelling pubmed-79904452021-04-14 COVID-19 Vaccination for Persons with Parkinson’s Disease: Light at the End of the Tunnel? Bloem, Bastiaan R. Trenkwalder, Claudia Sanchez-Ferro, Alvaro Kalia, Lorraine V. Alcalay, Roy Chiang, Han-Lin Kang, Un Jung Goetz, Christopher Brundin, Patrik Papa, Stella M. J Parkinsons Dis Commentary Several COVID-19 vaccines have recently been approved for emergency use according to governmental immunization programs. The arrival of these vaccines has created hope for people with Parkinson’s disease (PD), as this can help to mitigate their risk of becoming infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can lead to serious, life-threatening disease, at least among those with more advanced PD. However, both persons with PD and physicians looking after these individuals have expressed concerns about the vaccine’s efficacy and safety in the specific context of PD and its symptomatic treatment. Here, we discuss our perspective on these concerns, based on our interpretation of the literature plus the unfolding experience with widespread vaccination in the population at large. Because the benefits and risks of COVID-19 vaccines do not appear to be different than in the general population, we recommend COVID-19 vaccination with approved vaccines to persons with PD, unless there is a specific contraindication. Some caution seems warranted in very frail and terminally ill elderly persons with PD living in long-term care facilities. IOS Press 2021-02-02 /pmc/articles/PMC7990445/ /pubmed/33523021 http://dx.doi.org/10.3233/JPD-212573 Text en © 2021 – The authors. Published by IOS Press https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Bloem, Bastiaan R.
Trenkwalder, Claudia
Sanchez-Ferro, Alvaro
Kalia, Lorraine V.
Alcalay, Roy
Chiang, Han-Lin
Kang, Un Jung
Goetz, Christopher
Brundin, Patrik
Papa, Stella M.
COVID-19 Vaccination for Persons with Parkinson’s Disease: Light at the End of the Tunnel?
title COVID-19 Vaccination for Persons with Parkinson’s Disease: Light at the End of the Tunnel?
title_full COVID-19 Vaccination for Persons with Parkinson’s Disease: Light at the End of the Tunnel?
title_fullStr COVID-19 Vaccination for Persons with Parkinson’s Disease: Light at the End of the Tunnel?
title_full_unstemmed COVID-19 Vaccination for Persons with Parkinson’s Disease: Light at the End of the Tunnel?
title_short COVID-19 Vaccination for Persons with Parkinson’s Disease: Light at the End of the Tunnel?
title_sort covid-19 vaccination for persons with parkinson’s disease: light at the end of the tunnel?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990445/
https://www.ncbi.nlm.nih.gov/pubmed/33523021
http://dx.doi.org/10.3233/JPD-212573
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