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Phosphorylation and Dephosphorylation of Tau Protein by the Catalytic Subunit of PKA, as Probed by Electrophoretic Mobility Retard

BACKGROUND: Tau is a microtubule associated protein that regulates the stability of microtubules and the microtubule-dependent axonal transport. Its hyperphosphorylated form is one of the hallmarks of Alzheimer’s disease and other tauopathies and the major component of the paired helical filaments t...

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Detalles Bibliográficos
Autores principales: Benítez, María J., Cuadros, Raquel, Jiménez, Juan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990467/
https://www.ncbi.nlm.nih.gov/pubmed/33386804
http://dx.doi.org/10.3233/JAD-201077