Analysis of Factors Causing Skin Damage in the Application of Peripherally Inserted Central Catheter in Cancer Patients

OBJECTIVE: To investigate the related factors of skin damage caused by peripherally inserted central catheter (PICC) in cancer patients. METHODS: It was a retrospective analysis of 202 cancer patients admitted to our hospital from February 2014 to July 2019. 50 cases of PICC-related skin damage and 152 cases of non-skin damage were studied. In addition, multivariate logistic regression analysis was used to determine independent risk factors for PICC-related skin damage, including cancer patients with catheter-related skin damage and patients without skin damage. RESULTS: 50 patients with PICC skin damage (19 males and 31 females) and 152 patients without skin damage (62 males and 90 females) were retrospectively analyzed. The skin damage rate was 24.8%. The analysis of variance results showed that many factors are related to PICC catheter-related skin damage, including hormones (χ(2)/Z = 4.468, P < 0.05), body mass index (BMI) (χ(2)/Z = −2.443, P < 0.05), days with tube (χ(2) = 26.230, P < 0.05), chemotherapy cycle (χ(2)/Z = 25.638, P < 0.05), and self-care ability (χ(2)/Z = −1.968, P < 0.05). Logistic regression analysis showed that hormones (odds ratio (OR) = 3.896, P=0.045), BMI (OR = 1.129, P=0.017), days with tube (OR = 0.419, P=0.013), and chemotherapy cycle (OR = 3.302, P=0.028) are independent factors affecting PICC-related skin damage. CONCLUSION: The independent influencing factors of skin damage during PICC catheterization are hormones, BMI, number of days with tube, and chemotherapy cycle.