Role of Circular RNA in Kidney-Related Diseases

The kidney is vital in maintaining fluid, electrolyte, and acid–base balance. Kidney-related diseases, which are an increasing public health issue, can happen to people of any age and at any time. Circular RNAs (circRNAs) are endogenous RNA that are produced by selective RNA splicing and are involve...

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Autores principales: Chen, Xin-Tian, Li, Zhong-Wei, Zhao, Xue, Li, Min-Le, Hou, Ping-Fu, Chu, Su-Fang, Zheng, Jun-Nian, Bai, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990792/
https://www.ncbi.nlm.nih.gov/pubmed/33776764
http://dx.doi.org/10.3389/fphar.2021.615882
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author Chen, Xin-Tian
Li, Zhong-Wei
Zhao, Xue
Li, Min-Le
Hou, Ping-Fu
Chu, Su-Fang
Zheng, Jun-Nian
Bai, Jin
author_facet Chen, Xin-Tian
Li, Zhong-Wei
Zhao, Xue
Li, Min-Le
Hou, Ping-Fu
Chu, Su-Fang
Zheng, Jun-Nian
Bai, Jin
author_sort Chen, Xin-Tian
collection PubMed
description The kidney is vital in maintaining fluid, electrolyte, and acid–base balance. Kidney-related diseases, which are an increasing public health issue, can happen to people of any age and at any time. Circular RNAs (circRNAs) are endogenous RNA that are produced by selective RNA splicing and are involved in progression of various diseases. Studies have shown that various kidney diseases, including renal cell carcinoma, acute kidney injury, and chronic kidney disease, are linked to circRNAs. This review outlines the characteristics and biological functions of circRNAs and discusses specific studies that provide insights into the function and potential of circRNAs for application in the diagnosis and treatment of kidney-related diseases.
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spelling pubmed-79907922021-03-26 Role of Circular RNA in Kidney-Related Diseases Chen, Xin-Tian Li, Zhong-Wei Zhao, Xue Li, Min-Le Hou, Ping-Fu Chu, Su-Fang Zheng, Jun-Nian Bai, Jin Front Pharmacol Pharmacology The kidney is vital in maintaining fluid, electrolyte, and acid–base balance. Kidney-related diseases, which are an increasing public health issue, can happen to people of any age and at any time. Circular RNAs (circRNAs) are endogenous RNA that are produced by selective RNA splicing and are involved in progression of various diseases. Studies have shown that various kidney diseases, including renal cell carcinoma, acute kidney injury, and chronic kidney disease, are linked to circRNAs. This review outlines the characteristics and biological functions of circRNAs and discusses specific studies that provide insights into the function and potential of circRNAs for application in the diagnosis and treatment of kidney-related diseases. Frontiers Media S.A. 2021-03-11 /pmc/articles/PMC7990792/ /pubmed/33776764 http://dx.doi.org/10.3389/fphar.2021.615882 Text en Copyright © 2021 Chen, Li, Zhao, Li, Hou, Chu, Zheng and Bai. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Chen, Xin-Tian
Li, Zhong-Wei
Zhao, Xue
Li, Min-Le
Hou, Ping-Fu
Chu, Su-Fang
Zheng, Jun-Nian
Bai, Jin
Role of Circular RNA in Kidney-Related Diseases
title Role of Circular RNA in Kidney-Related Diseases
title_full Role of Circular RNA in Kidney-Related Diseases
title_fullStr Role of Circular RNA in Kidney-Related Diseases
title_full_unstemmed Role of Circular RNA in Kidney-Related Diseases
title_short Role of Circular RNA in Kidney-Related Diseases
title_sort role of circular rna in kidney-related diseases
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990792/
https://www.ncbi.nlm.nih.gov/pubmed/33776764
http://dx.doi.org/10.3389/fphar.2021.615882
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