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Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals
To moderate fast neutrons produced by accelerator to appropriate therapeutic energies for boron neutron capture therapy (BNCT), beam shaping assembly (BSA) is required definitely. In this work, based on a model of 2.5 MeV/30 mA proton accelerator, the Monte Carlo simulation software MCNPX was employ...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991290/ https://www.ncbi.nlm.nih.gov/pubmed/33777888 http://dx.doi.org/10.3389/fpubh.2021.642561 |
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author | Li, Guangru Jiang, Wei Zhang, Lu Chen, Weiqiang Li, Qiang |
author_facet | Li, Guangru Jiang, Wei Zhang, Lu Chen, Weiqiang Li, Qiang |
author_sort | Li, Guangru |
collection | PubMed |
description | To moderate fast neutrons produced by accelerator to appropriate therapeutic energies for boron neutron capture therapy (BNCT), beam shaping assembly (BSA) is required definitely. In this work, based on a model of 2.5 MeV/30 mA proton accelerator, the Monte Carlo simulation software MCNPX was employed to design multi-terminal BSAs. All parameters for both the thermal and epithermal neutron beams at the exit ports of the designed BSAs meet the treatment recommendation values proposed by the International Atomic Energy Agency (IAEA). The clinical parameters of the thermal and epithermal neutron beams were also calculated for clinical indication consideration. |
format | Online Article Text |
id | pubmed-7991290 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79912902021-03-26 Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals Li, Guangru Jiang, Wei Zhang, Lu Chen, Weiqiang Li, Qiang Front Public Health Public Health To moderate fast neutrons produced by accelerator to appropriate therapeutic energies for boron neutron capture therapy (BNCT), beam shaping assembly (BSA) is required definitely. In this work, based on a model of 2.5 MeV/30 mA proton accelerator, the Monte Carlo simulation software MCNPX was employed to design multi-terminal BSAs. All parameters for both the thermal and epithermal neutron beams at the exit ports of the designed BSAs meet the treatment recommendation values proposed by the International Atomic Energy Agency (IAEA). The clinical parameters of the thermal and epithermal neutron beams were also calculated for clinical indication consideration. Frontiers Media S.A. 2021-03-11 /pmc/articles/PMC7991290/ /pubmed/33777888 http://dx.doi.org/10.3389/fpubh.2021.642561 Text en Copyright © 2021 Li, Jiang, Zhang, Chen and Li. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Li, Guangru Jiang, Wei Zhang, Lu Chen, Weiqiang Li, Qiang Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals |
title | Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals |
title_full | Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals |
title_fullStr | Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals |
title_full_unstemmed | Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals |
title_short | Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals |
title_sort | design of beam shaping assemblies for accelerator-based bnct with multi-terminals |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991290/ https://www.ncbi.nlm.nih.gov/pubmed/33777888 http://dx.doi.org/10.3389/fpubh.2021.642561 |
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