Cargando…

Potentiation of Brain-Derived Neurotrophic Factor-Induced Protection of Spiral Ganglion Neurons by C3 Exoenzyme/Rho Inhibitor

Preservation of the excitability of spiral ganglion neurons (SGN) may contribute to an improved speech perception after cochlear implantation. Thus, the application of exogenous neurotrophic factors such as the neurotrophin brain-derived neurotrophic factor (BDNF) to increase SGN survival in vitro a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harre, Jennifer, Heinkele, Laura, Steffens, Melanie, Warnecke, Athanasia, Lenarz, Thomas, Just, Ingo, Rohrbeck, Astrid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991574/ https://www.ncbi.nlm.nih.gov/pubmed/33776650 http://dx.doi.org/10.3389/fncel.2021.602897

Ejemplares similares

Corrigendum: Potentiation of brain-derived neurotrophic factor-induced protection of spiral ganglion neurons by C3 exoenzyme/Rho inhibitor
por: Harre, Jennifer, et al.
Publicado: (2022)

Cell Entry of C3 Exoenzyme from Clostridium botulinum
por: Rohrbeck, Astrid, et al.
Publicado: (2016)

The Rho ADP-ribosylating C3 exoenzyme binds cells via an Arg–Gly–Asp motif
por: Rohrbeck, Astrid, et al.
Publicado: (2017)

Vimentin Mediates Uptake of C3 Exoenzyme
por: Rohrbeck, Astrid, et al.
Publicado: (2014)

C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors
por: von Elsner, Leonie, et al.
Publicado: (2016)

Anti-proliferative Effect of C3 Exoenzyme in Fibroblasts is Mediated by c-Jun Phosphorylation
por: von Elsner, Leonie, et al.
Publicado: (2017)

Long-term delivery of brain-derived neurotrophic factor (BDNF) from nanoporous silica nanoparticles improves the survival of spiral ganglion neurons in vitro
por: Schmidt, Nadeschda, et al.
Publicado: (2018)

Phosphodiesterase Type 4 Inhibitor Rolipram Improves Survival of Spiral Ganglion Neurons In Vitro
por: Kranz, Katharina, et al.
Publicado: (2014)

Neuronal Survival, Morphology and Outgrowth of Spiral Ganglion Neurons Using a Defined Growth Factor Combination
por: Schwieger, Jana, et al.
Publicado: (2015)

Uptake of Clostridium botulinum C3 Exoenzyme into Intact HT22 and J774A.1 Cells
por: Rohrbeck, Astrid, et al.
Publicado: (2015)

Coatings of Different Carbon Nanotubes on Platinum Electrodes for Neuronal Devices: Preparation, Cytocompatibility and Interaction with Spiral Ganglion Cells
por: Burblies, Niklas, et al.
Publicado: (2016)

The Higher Sensitivity of GABAergic Compared to Glutamatergic Neurons to Growth-Promoting C3bot Treatment Is Mediated by Vimentin
por: Adolf, Andrej, et al.
Publicado: (2020)

Purification of Fibroblasts From the Spiral Ganglion
por: Anacker, Annett, et al.
Publicado: (2022)

Innate Immunity to Spiral Ganglion Neuron Loss: A Neuroprotective Role of Fractalkine Signaling in Injured Cochlea
por: Stothert, Andrew Rigel, et al.
Publicado: (2021)

Intrinsically Self-renewing Neuroprogenitors From the A/J Mouse Spiral Ganglion as Virtually Unlimited Source of Mature Auditory Neurons
por: Rousset, Francis, et al.
Publicado: (2020)

Effect of Immunophilin Inhibitors on Cochlear Fibroblasts and Spiral Ganglion Cells
por: Goblet, Madeleine, et al.
Publicado: (2023)

Decellularized equine carotid artery layers as matrix for regenerated neurites of spiral ganglion neurons
por: Yilmaz-Bayraktar, Suheda, et al.
Publicado: (2019)

The Three-Dimensional Culture System with Matrigel and Neurotrophic Factors Preserves the Structure and Function of Spiral Ganglion Neuron In Vitro
por: Sun, Gaoying, et al.
Publicado: (2016)

Development of Neuronal Guidance Fibers for Stimulating Electrodes: Basic Construction and Delivery of a Growth Factor
por: Wille, Inga, et al.
Publicado: (2022)

Detection and Quantification of ADP-Ribosylated RhoA/B by Monoclonal Antibody
por: Rohrbeck, Astrid, et al.
Publicado: (2016)

Protective Effect of Edaravone on Glutamate-Induced Neurotoxicity in Spiral Ganglion Neurons
por: Bai, Xiaohui, et al.
Publicado: (2016)

Similarities in the Biophysical Properties of Spiral-Ganglion and Vestibular-Ganglion Neurons in Neonatal Rats
por: Kalluri, Radha
Publicado: (2021)

Mechanism and Prevention of Spiral Ganglion Neuron Degeneration in the Cochlea
por: Zhang, Li, et al.
Publicado: (2022)

“Of mice and men”: the relevance of Cometin and Erythropoietin origin for its effects on murine spiral ganglion neuron survival and neurite outgrowth in vitro
por: Schwieger, Jana, et al.
Publicado: (2023)

Generation of a Spiral Ganglion Neuron Degeneration Mouse Model
por: Hu, Zhengqing, et al.
Publicado: (2021)

Phosphorus deficiencies invoke optimal allocation of exoenzymes by ectomycorrhizas
por: Meeds, Justin A., et al.
Publicado: (2021)

Functional Pattern of Increasing Concentrations of Brain-Derived Neurotrophic Factor in Spiral Ganglion: Implications for Research on Cochlear Implants
por: Ramku, Emina, et al.
Publicado: (2017)

Considering the protective effect of exendin-4 against oxidative stress in spiral ganglion neurons
por: Wu, Hongxia, et al.
Publicado: (2023)

Editorial: Rho family GTPases and their effectors in neuronal survival and neurodegeneration
por: Linseman, Daniel A., et al.
Publicado: (2023)

Spiral Ganglion Neuron Explant Culture and Electrophysiology on Multi Electrode Arrays
por: Hahnewald, Stefan, et al.
Publicado: (2016)

Spiral Ganglion Stem Cells Can Be Propagated and Differentiated Into Neurons and Glia
por: Diensthuber, Marc, et al.
Publicado: (2014)

Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages
por: Li, Chao, et al.
Publicado: (2020)

Developmental Changes in Peripherin-eGFP Expression in Spiral Ganglion Neurons
por: Elliott, Karen L., et al.
Publicado: (2021)

Pericytes control vascular stability and auditory spiral ganglion neuron survival
por: Zhang, Yunpei, et al.
Publicado: (2023)

Specification of neuronal subtypes in the spiral ganglion begins prior to birth in the mouse
por: Sanders, Tessa R., et al.
Publicado: (2022)

486 Molecular Mechanisms of Type II Spiral Ganglion Neuron Development
por: George, Deborah Jane, et al.
Publicado: (2023)

Enhancement of Phosphorylation and Transport Activity of the Neuronal Glutamate Transporter Excitatory Amino Acid Transporter 3 by C3bot and a 26mer C3bot Peptide
por: Piepgras, Johannes, et al.
Publicado: (2022)

Personalized Proteomics for Precision Diagnostics in Hearing Loss: Disease-Specific Analysis of Human Perilymph by Mass Spectrometry
por: Schmitt, Heike A., et al.
Publicado: (2021)

Enhanced Survival of Spiral Ganglion Cells After Cessation of Treatment with Brain-Derived Neurotrophic Factor in Deafened Guinea Pigs
por: Agterberg, Martijn J. H., et al.
Publicado: (2009)

Protective effect of adenovirus-mediated erythropoietin expression on the spiral ganglion neurons in the rat inner ear
por: Zhong, Cheng, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tao5a4rfdsnsegnarftm3kmk7g