FGF1(ΔHBS) prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression

As a classically known mitogen, fibroblast growth factor 1 (FGF1) has been found to exert other pleiotropic functions such as metabolic regulation and myocardial protection. Here, we show that serum levels of FGF1 were decreased and positively correlated with fraction shortening in diabetic cardiomy...

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Detalles Bibliográficos
Autores principales: Wang, Dezhong, Yin, Yuan, Wang, Shuyi, Zhao, Tianyang, Gong, Fanghua, Zhao, Yushuo, Wang, Beibei, Huang, Yuli, Cheng, Zizhao, Zhu, Guanghui, Wang, Zengshou, Wang, Yang, Ren, Jun, Liang, Guang, Li, Xiaokun, Huang, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991671/
https://www.ncbi.nlm.nih.gov/pubmed/33762571
http://dx.doi.org/10.1038/s41392-021-00542-2

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