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A Pilot Study Investigating the Use of Regional Oxygen Saturation as a Predictor of Ischemic Wound Healing Outcome after Endovascular Treatment in Patients with Chronic Limb-Threatening Ischemia
Objective: To determine the prognostic value of regional tissue oxygenation saturation (rSO(2)) for ulcer healing after endovascular treatment (EVT) of peripheral arterial disease (PAD). Materials and Methods: Among PAD patients, 34 patients with chronic limb-threatening ischemia underwent EVT for l...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese College of Angiology / The Japanese Society for Vascular Surgery / Japanese Society of Phlebology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991714/ https://www.ncbi.nlm.nih.gov/pubmed/33786096 http://dx.doi.org/10.3400/avd.oa.20-00132 |
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author | Kayama, Takafumi Sano, Masaki Inuzuka, Kazunori Katahashi, Kazuto Yata, Tatsuro Yamanaka, Yuta Naruse, Ena Yamamoto, Naoto Takeuchi, Hiroya Unno, Naoki |
author_facet | Kayama, Takafumi Sano, Masaki Inuzuka, Kazunori Katahashi, Kazuto Yata, Tatsuro Yamanaka, Yuta Naruse, Ena Yamamoto, Naoto Takeuchi, Hiroya Unno, Naoki |
author_sort | Kayama, Takafumi |
collection | PubMed |
description | Objective: To determine the prognostic value of regional tissue oxygenation saturation (rSO(2)) for ulcer healing after endovascular treatment (EVT) of peripheral arterial disease (PAD). Materials and Methods: Among PAD patients, 34 patients with chronic limb-threatening ischemia underwent EVT for limb salvage. We retrospectively analyzed the cutoff rSO(2) values on postoperative day 1 to predict ulcer healing and patient prognosis. Skin perfusion pressure (SPP) and transcutaneous oxygen pressure (TcPO(2)) were also used to assess wound healing. Results: A finger-mounted tissue oximeter can easily measure rSO(2) on the dorsal foot. Among the 34 patients, the ulcer healed in 25, and no changes were observed in 2 patients at 1 month after EVT. However, 7 patients needed major amputation at the same time. Wound healing was achieved in all patients with rSO(2)≥50%. With this cutoff, the sensitivity and specificity of the new device for wound healing were 100% and 64%, respectively. In all the wound healing cases, SPP was ≥45 mmHg, and TcPO(2) was ≥40 mmHg. Conclusion: To assess limb ischemia, rSO(2) can be measured quickly and easily using this device. We suggest that an rSO(2)>50% shows good prognosis for ulcer healing. |
format | Online Article Text |
id | pubmed-7991714 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Japanese College of Angiology / The Japanese Society for Vascular Surgery / Japanese Society of Phlebology |
record_format | MEDLINE/PubMed |
spelling | pubmed-79917142021-03-29 A Pilot Study Investigating the Use of Regional Oxygen Saturation as a Predictor of Ischemic Wound Healing Outcome after Endovascular Treatment in Patients with Chronic Limb-Threatening Ischemia Kayama, Takafumi Sano, Masaki Inuzuka, Kazunori Katahashi, Kazuto Yata, Tatsuro Yamanaka, Yuta Naruse, Ena Yamamoto, Naoto Takeuchi, Hiroya Unno, Naoki Ann Vasc Dis Original Article Objective: To determine the prognostic value of regional tissue oxygenation saturation (rSO(2)) for ulcer healing after endovascular treatment (EVT) of peripheral arterial disease (PAD). Materials and Methods: Among PAD patients, 34 patients with chronic limb-threatening ischemia underwent EVT for limb salvage. We retrospectively analyzed the cutoff rSO(2) values on postoperative day 1 to predict ulcer healing and patient prognosis. Skin perfusion pressure (SPP) and transcutaneous oxygen pressure (TcPO(2)) were also used to assess wound healing. Results: A finger-mounted tissue oximeter can easily measure rSO(2) on the dorsal foot. Among the 34 patients, the ulcer healed in 25, and no changes were observed in 2 patients at 1 month after EVT. However, 7 patients needed major amputation at the same time. Wound healing was achieved in all patients with rSO(2)≥50%. With this cutoff, the sensitivity and specificity of the new device for wound healing were 100% and 64%, respectively. In all the wound healing cases, SPP was ≥45 mmHg, and TcPO(2) was ≥40 mmHg. Conclusion: To assess limb ischemia, rSO(2) can be measured quickly and easily using this device. We suggest that an rSO(2)>50% shows good prognosis for ulcer healing. Japanese College of Angiology / The Japanese Society for Vascular Surgery / Japanese Society of Phlebology 2021-03-25 /pmc/articles/PMC7991714/ /pubmed/33786096 http://dx.doi.org/10.3400/avd.oa.20-00132 Text en © 2021 The Editorial Committee of Annals of Vascular Diseases. http://creativecommons.org/licenses/by/2.5/ This article is distributed under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided the credit of the original work, a link to the license, and indication of any change are properly given, and the original work is not used for commercial purposes. Remixed or transformed contributions must be distributed under the same license as the original. |
spellingShingle | Original Article Kayama, Takafumi Sano, Masaki Inuzuka, Kazunori Katahashi, Kazuto Yata, Tatsuro Yamanaka, Yuta Naruse, Ena Yamamoto, Naoto Takeuchi, Hiroya Unno, Naoki A Pilot Study Investigating the Use of Regional Oxygen Saturation as a Predictor of Ischemic Wound Healing Outcome after Endovascular Treatment in Patients with Chronic Limb-Threatening Ischemia |
title | A Pilot Study Investigating the Use of Regional Oxygen Saturation as a Predictor of Ischemic Wound Healing Outcome after Endovascular Treatment in Patients with Chronic Limb-Threatening Ischemia |
title_full | A Pilot Study Investigating the Use of Regional Oxygen Saturation as a Predictor of Ischemic Wound Healing Outcome after Endovascular Treatment in Patients with Chronic Limb-Threatening Ischemia |
title_fullStr | A Pilot Study Investigating the Use of Regional Oxygen Saturation as a Predictor of Ischemic Wound Healing Outcome after Endovascular Treatment in Patients with Chronic Limb-Threatening Ischemia |
title_full_unstemmed | A Pilot Study Investigating the Use of Regional Oxygen Saturation as a Predictor of Ischemic Wound Healing Outcome after Endovascular Treatment in Patients with Chronic Limb-Threatening Ischemia |
title_short | A Pilot Study Investigating the Use of Regional Oxygen Saturation as a Predictor of Ischemic Wound Healing Outcome after Endovascular Treatment in Patients with Chronic Limb-Threatening Ischemia |
title_sort | pilot study investigating the use of regional oxygen saturation as a predictor of ischemic wound healing outcome after endovascular treatment in patients with chronic limb-threatening ischemia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991714/ https://www.ncbi.nlm.nih.gov/pubmed/33786096 http://dx.doi.org/10.3400/avd.oa.20-00132 |
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