Cargando…

Diet-Dependent Changes of the DNA Methylome Using a Göttingen Minipig Model for Obesity

Objective: Environmental factors can influence obesity by epigenetic mechanisms. The aim of this study was to investigate obesity-related epigenetic changes and the potential for reversal of these changes in the liver of Göttingen minipigs subjected to diet interventions. Methods: High-throughput li...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Y., Cirera, S., Taşöz, E., Liu, Y., Olsen, L. H., Christoffersen, B. Ø., Pedersen, H. D., Ludvigsen, T. P., Kirk, R. K., Schumacher-Petersen, C., Deng, Y., Fredholm, M., Gao, F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991730/ https://www.ncbi.nlm.nih.gov/pubmed/33777102 http://dx.doi.org/10.3389/fgene.2021.632859

Ejemplares similares

The expression signatures in liver and adipose tissue from obese Göttingen Minipigs reveal a predisposition for healthy fat accumulation
por: Cirera, Susanna, et al.
Publicado: (2020)

NASH-inducing Diets in Göttingen Minipigs
por: Pedersen, Henrik D., et al.
Publicado: (2020)

Experimental non-alcoholic steatohepatitis in Göttingen Minipigs: consequences of high fat-fructose-cholesterol diet and diabetes
por: Schumacher-Petersen, Camilla, et al.
Publicado: (2019)

Functional and morphological renal changes in a Göttingen Minipig model of obesity-related and diabetic nephropathy
por: Christoffersen, Berit Østergaard, et al.
Publicado: (2023)

Characterisation of Gut Microbiota in Ossabaw and Göttingen Minipigs as Models of Obesity and Metabolic Syndrome
por: Pedersen, Rebecca, et al.
Publicado: (2013)

Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals
por: Ludvigsen, Trine Pagh, et al.
Publicado: (2015)

Dietary normalization from a fat, fructose and cholesterol-rich diet to chow limits the amount of myocardial collagen in a Göttingen Minipig model of obesity
por: Andreasen, Laura Jul, et al.
Publicado: (2018)

Joint Profiling of miRNAs and mRNAs Reveals miRNA Mediated Gene Regulation in the Göttingen Minipig Obesity Model
por: Mentzel, Caroline M. Junker, et al.
Publicado: (2016)

Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model
por: Lützhøft, Ditte Olsen, et al.
Publicado: (2022)

Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected
por: Christiansen, Liselotte Bruun, et al.
Publicado: (2021)

Nanopore sequencing reveals methylation changes associated with obesity in circulating cell-free DNA from Göttingen Minipigs
por: Drag, Markus Hodal, et al.
Publicado: (2023)

Spontaneous Object Recognition in the Göttingen Minipig
por: Moustgaard, Anette, et al.
Publicado: (2002)

Assessing breed integrity of Göttingen Minipigs
por: Reimer, Christian, et al.
Publicado: (2020)

Online histological atlas of the Göttingen minipig brain
por: Orlowski, Dariusz, et al.
Publicado: (2019)

Long-acting CCK analogue NN9056 lowers food intake and body weight in obese Göttingen Minipigs
por: Christoffersen, Berit Ø., et al.
Publicado: (2019)

Determination of Odor Detection Threshold in the Göttingen Minipig
por: Søndergaard, Lene Vammen, et al.
Publicado: (2010)

Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs
por: Renner, Simone, et al.
Publicado: (2018)

High Fat, Low Carbohydrate Diet Limit Fear and Aggression in Göttingen Minipigs
por: Haagensen, Annika Maria Juul, et al.
Publicado: (2014)

The Retrograde Connections and Anatomical Segregation of the Göttingen Minipig Nucleus Accumbens
por: Meidahl, Anders C., et al.
Publicado: (2016)

Functional analysis and transcriptional output of the Göttingen minipig genome
por: Heckel, Tobias, et al.
Publicado: (2015)

Hyperinsulinaemic hypoglycaemia in non-anaesthetized Göttingen minipigs induces a counter-regulatory endocrine response and electrocardiographic changes
por: Lyhne, Mille K., et al.
Publicado: (2021)

POLYRETINA restores light responses in vivo in blind Göttingen minipigs
por: Vagni, Paola, et al.
Publicado: (2022)

Obesity Development and Signs of Metabolic Abnormalities in Young Göttingen Minipigs Consuming Energy Dense Diets Varying in Carbohydrate Quality
por: Curtasu, Mihai Victor, et al.
Publicado: (2021)

Cognitive Performance of Göttingen Minipigs Is Affected by Diet in a Spatial Hole-Board Discrimination Test
por: Haagensen, Annika Maria Juul, et al.
Publicado: (2013)

Effects of Anesthesia and Species on the Uptake or Binding of Radioligands In Vivo in the Göttingen Minipig
por: Alstrup, Aage K. O., et al.
Publicado: (2013)

Cerebrospinal Fluid Characterization in Cynomolgus Monkeys, Beagle Dogs, and Göttingen Minipigs
por: Ballesteros, Cristina, et al.
Publicado: (2020)

Characterization and Pharmacological Validation of a Preclinical Model of NASH in Göttingen Minipigs
por: Duvivier, Valérie, et al.
Publicado: (2022)

Effects of captopril against radiation injuries in the Göttingen minipig model of hematopoietic-acute radiation syndrome
por: Rittase, W. Bradley, et al.
Publicado: (2021)

Towards a Göttingen minipig model of adult onset growth hormone deficiency: evaluation of stereotactic electrocoagulation method
por: Ørstrup, Laura Hvidsten, et al.
Publicado: (2019)

Hematological Changes as Prognostic Indicators of Survival: Similarities Between Gottingen Minipigs, Humans, and Other Large Animal Models
por: Moroni, Maria, et al.
Publicado: (2011)

Soman-induced toxicity, cholinesterase inhibition and neuropathology in adult male Göttingen minipigs()
por: Lumley, Lucille, et al.
Publicado: (2021)

No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs
por: Kleinbongard, Petra, et al.
Publicado: (2023)

First virological and pathological study of Göttingen Minipigs with Dippity Pig Syndrome (DPS)
por: Jhelum, Hina, et al.
Publicado: (2023)

Hepatic regeneration following radiation-induced liver injury is associated with increased hepatobiliary secretion measured by PET in Göttingen minipigs
por: Kjærgaard, Kristoffer, et al.
Publicado: (2020)

Basic Surgical Techniques in the Göttingen Minipig: Intubation, Bladder Catheterization, Femoral Vessel Catheterization, and Transcardial Perfusion
por: Ettrup, Kaare S., et al.
Publicado: (2011)

Response to Novelty Correlates with Learning Rate in a Go/No-Go Task in Göttingen Minipigs
por: Lind, Nanna Marie, et al.
Publicado: (2005)

Application of Immunohistochemistry in Stereology for Quantitative Assessment of Neural Cell Populations Illustrated in the Göttingen Minipig
por: Hou, Jack, et al.
Publicado: (2012)

Experimental articular cartilage repair in the Göttingen minipig: the influence of multiple defects per knee
por: Christensen, Bjørn Borsøe, et al.
Publicado: (2015)

A minimally-invasive serial cerebrospinal fluid sampling model in conscious Göttingen minipigs
por: Bergadano, Alessandra, et al.
Publicado: (2019)

Exploring the K isotope composition of Göttingen minipig brain regions, and implications for Alzheimer's disease
por: Mahan, Brandon, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_33o7e9brsdd3g170lg1cpsn6p5