Cargando…

LncRNA MEG3 Protects Chondrocytes From IL-1β-Induced Inflammation via Regulating miR-9-5p/KLF4 Axis

BACKGROUND: Osteoarthritis (OA) is a chronic degenerative disease of the joints characterized by articular cartilage damage, subchondral bone remodeling, osteophyte formation, and inflammatory changes. This work aims to investigate the protective role of long non-coding RNA (lncRNA) maternally expre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Yijiang, Chen, Daosen, Yan, Zijian, Zhan, Jingdi, Xue, Xinghe, Pan, Xiaoyun, Yu, Huachen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991831/ https://www.ncbi.nlm.nih.gov/pubmed/33776787 http://dx.doi.org/10.3389/fphys.2021.617654

Ejemplares similares

Bone marrow mesenchymal stem cell–derived exosomal miR‐206 promotes osteoblast proliferation and differentiation in osteoarthritis by reducing Elf3
por: Huang, Yijiang, et al.
Publicado: (2021)

Lycopene inhibits IL‐1β‐induced inflammation in mouse chondrocytes and mediates murine osteoarthritis
por: Zhan, Jingdi, et al.
Publicado: (2021)

The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head
por: Yan, Zijian, et al.
Publicado: (2020)

LncRNA MEG3 inhibits the development of nasopharyngeal carcinoma by sponging miR-543 targeting KLF4
por: Ning, Jiayu, et al.
Publicado: (2020)

lncRNA MEG8 is downregulated in osteoarthritis and regulates chondrocyte cell proliferation, apoptosis and inflammation
por: Xie, Wei, et al.
Publicado: (2021)

Effect of lncRNA PVT1/miR186/KLF5 Axis on the Occurrence and Progression of Cholangiocarcinoma
por: Sun, Qiang, et al.
Publicado: (2021)

The lncRNA MEG3 downregulation leads to osteoarthritis progression via miR-16/SMAD7 axis
por: Xu, Jin, et al.
Publicado: (2017)

Tumor-Suppressive Function of lncRNA-MEG3 in Glioma Cells by Regulating miR-6088/SMARCB1 Axis
por: Gong, Xin, et al.
Publicado: (2020)

LncRNA MEG3 promotes cisplatin sensitivity of cervical cancer cells by regulating the miR-21/PTEN axis
por: Du, Ying, et al.
Publicado: (2022)

Exosomal microRNA-140-3p from human umbilical cord mesenchymal stem cells attenuates joint injury of rats with rheumatoid arthritis by silencing SGK1
por: Huang, Yijiang, et al.
Publicado: (2022)

LncRNA LUCAT1/miR-181a-5p axis promotes proliferation and invasion of breast cancer via targeting KLF6 and KLF15
por: Liu, Yun, et al.
Publicado: (2020)

LncRNA MEG3 inhibits the progression of prostate cancer by modulating miR‐9‐5p/QKI‐5 axis
por: Wu, Meng, et al.
Publicado: (2018)

LncRNA MEG3 promotes melanoma growth, metastasis and formation through modulating miR-21/E-cadherin axis
por: Wu, Liangcai, et al.
Publicado: (2020)

Knockdown of lncRNA JPX suppresses IL-1β-stimulated injury in chondrocytes through modulating an miR-25-3p/PPID axis
por: Ren, Zhiyong, et al.
Publicado: (2022)

Anisomycin inhibits angiogenesis in ovarian cancer by attenuating the molecular sponge effect of the lncRNA-Meg3/miR-421/PDGFRA axis
por: Ye, Weiping, et al.
Publicado: (2019)

Correction to: LncRNA MEG3 promotes melanoma growth, metastasis and formation through modulating miR-21/E-cadherin axis
por: Wu, Liangcai, et al.
Publicado: (2020)

IL-27 induces autophagy through regulation of the DNMT1/lncRNA MEG3/ERK/p38 axis to reduce pulmonary fibrosis
por: Ting, Li, et al.
Publicado: (2023)

Activating Nrf2 signalling alleviates osteoarthritis development by inhibiting inflammasome activation
por: Yan, Zijian, et al.
Publicado: (2020)

LncRNA MEG3 influences the proliferation and apoptosis of psoriasis epidermal cells by targeting miR-21/caspase-8
por: Jia, Hai-Yan, et al.
Publicado: (2019)

lncRNA MEG3 Suppresses the Progression of Ankylosis Spondylitis by Regulating the Let-7i/SOST Axis
por: Ma, Junjie, et al.
Publicado: (2020)

LncRNA MEG3 inhibits cell proliferation and induces apoptosis in laryngeal cancer via miR‐23a/APAF‐1 axis
por: Zhang, Xiaowen, et al.
Publicado: (2019)

LncRNA HAGLR silencing inhibits IL-1β-induced chondrocytes inflammatory injury via miR-130a-3p/JAK1 axis
por: Zuo, Yunzhou, et al.
Publicado: (2023)

lncRNA HAND2-AS1 is downregulated in osteoarthritis and regulates IL-6 expression in chondrocytes
por: Si, Zhenxing, et al.
Publicado: (2021)

The Association of MEG3 lncRNA with Nuclear Speckles in Living Cells
por: Hasenson, Sarah E., et al.
Publicado: (2022)

A review on the role of MEG8 lncRNA in human disorders
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2022)

LncRNA POU3F3 promotes melanoma cell proliferation by downregulating lncRNA MEG3
por: Liu, Yingnan, et al.
Publicado: (2021)

lncRNA MEG3 Promotes PDK4/GSK-3β/β-Catenin Axis in MEFs by Targeting miR-532-5p
por: Yang, Yuan-Yuan, et al.
Publicado: (2023)

Depletion of lncRNA MEG3 Ameliorates Imatinib-Induced Injury of Cardiomyocytes via Regulating miR-129-5p/HMGB1 Axis
por: Tang, Peng, et al.
Publicado: (2023)

Silencing of lncRNA KLF3‐AS1 represses cell growth in osteosarcoma via miR‐338‐3p/MEF2C axis
por: Chen, Chunfa, et al.
Publicado: (2022)

lncRNA KLF3-AS1 Suppresses Cell Migration and Invasion in ESCC by Impairing miR-185-5p-Targeted KLF3 Inhibition
por: Liu, Jun-Qi, et al.
Publicado: (2020)

LncRNA MEG8 promotes NSCLC progression by modulating the miR-15a-5p-miR-15b-5p/PSAT1 axis
por: Guo, Kai, et al.
Publicado: (2021)

LncRNA HLA-F-AS1 Enhances the Migration, Invasion and Apoptosis of Glioblastoma Cells by Targeting lncRNA MEG3
por: Wang, Yanhua, et al.
Publicado: (2021)

LncRNA PACER is down-regulated in osteoarthritis and regulates chondrocyte apoptosis and lncRNA HOTAIR expression
por: Jiang, Mingwei, et al.
Publicado: (2019)

lncRNA OIP5-AS1 attenuates the osteoarthritis progression in IL-1β-stimulated chondrocytes
por: Zhang, Xuefeng, et al.
Publicado: (2023)

MEG3 promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-361-5p/FOXO1 axis
por: Wang, Anying, et al.
Publicado: (2019)

Methylene blue relieves the development of osteoarthritis by upregulating lncRNA MEG3
por: Li, Xinyi, et al.
Publicado: (2018)

Hypermethylation of lncRNA MEG3 impairs chemosensitivity of breast cancer cells
por: Li, Hongchang, et al.
Publicado: (2020)

LncRNA MEG3: Potential stock for precision treatment of cardiovascular diseases
por: Li, Zining, et al.
Publicado: (2022)

LncRNA-MEG3 inhibits activation of hepatic stellate cells through SMO protein and miR-212
por: Yu, Fujun, et al.
Publicado: (2018)

LncRNA MEG3 enhances cisplatin sensitivity in non-small cell lung cancer by regulating miR-21-5p/SOX7 axis
por: Wang, Pei, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_hl5jenf7mgh1mc4na0r1j7jrl1