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Is Malaysia Ready for Human Gene Editing: A Regulatory, Biosafety and Biosecurity Perspective

Gene editing platforms have revolutionized the field of genetics with a direct impact on the public health system. Although there are apparent benefits, it is often accompanied by public debates over its uncertainties and risks. In the Malaysian context, modern biotechnology has raised questions abo...

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Autores principales: Kalidasan, V., Theva Das, Kumitaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992004/
https://www.ncbi.nlm.nih.gov/pubmed/33777918
http://dx.doi.org/10.3389/fbioe.2021.649203
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author Kalidasan, V.
Theva Das, Kumitaa
author_facet Kalidasan, V.
Theva Das, Kumitaa
author_sort Kalidasan, V.
collection PubMed
description Gene editing platforms have revolutionized the field of genetics with a direct impact on the public health system. Although there are apparent benefits, it is often accompanied by public debates over its uncertainties and risks. In the Malaysian context, modern biotechnology has raised questions about how to best govern gene editing in regulations, biosafety, and biosecurity. Even though standards and guidelines on stem cell and cell-based therapies have been developed, there are no appropriate legal frameworks available for gene editing yet. Nevertheless, biosafety regulations were established to balance promoting biotechnology and protecting against their potential environmental and human health risks. There is also a need to address the potential of genetically modified organisms (GMOs) as bioweapons. Numerous frameworks from several international organizations may provide valuable input in formulating documents on gene editing. By establishing comprehensive guidelines, legal policies, and standards to tackle the challenges and risks associated with gene editing, Malaysia can successfully apply this modern technology in this country.
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spelling pubmed-79920042021-03-26 Is Malaysia Ready for Human Gene Editing: A Regulatory, Biosafety and Biosecurity Perspective Kalidasan, V. Theva Das, Kumitaa Front Bioeng Biotechnol Bioengineering and Biotechnology Gene editing platforms have revolutionized the field of genetics with a direct impact on the public health system. Although there are apparent benefits, it is often accompanied by public debates over its uncertainties and risks. In the Malaysian context, modern biotechnology has raised questions about how to best govern gene editing in regulations, biosafety, and biosecurity. Even though standards and guidelines on stem cell and cell-based therapies have been developed, there are no appropriate legal frameworks available for gene editing yet. Nevertheless, biosafety regulations were established to balance promoting biotechnology and protecting against their potential environmental and human health risks. There is also a need to address the potential of genetically modified organisms (GMOs) as bioweapons. Numerous frameworks from several international organizations may provide valuable input in formulating documents on gene editing. By establishing comprehensive guidelines, legal policies, and standards to tackle the challenges and risks associated with gene editing, Malaysia can successfully apply this modern technology in this country. Frontiers Media S.A. 2021-03-11 /pmc/articles/PMC7992004/ /pubmed/33777918 http://dx.doi.org/10.3389/fbioe.2021.649203 Text en Copyright © 2021 Kalidasan and Theva Das. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Kalidasan, V.
Theva Das, Kumitaa
Is Malaysia Ready for Human Gene Editing: A Regulatory, Biosafety and Biosecurity Perspective
title Is Malaysia Ready for Human Gene Editing: A Regulatory, Biosafety and Biosecurity Perspective
title_full Is Malaysia Ready for Human Gene Editing: A Regulatory, Biosafety and Biosecurity Perspective
title_fullStr Is Malaysia Ready for Human Gene Editing: A Regulatory, Biosafety and Biosecurity Perspective
title_full_unstemmed Is Malaysia Ready for Human Gene Editing: A Regulatory, Biosafety and Biosecurity Perspective
title_short Is Malaysia Ready for Human Gene Editing: A Regulatory, Biosafety and Biosecurity Perspective
title_sort is malaysia ready for human gene editing: a regulatory, biosafety and biosecurity perspective
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992004/
https://www.ncbi.nlm.nih.gov/pubmed/33777918
http://dx.doi.org/10.3389/fbioe.2021.649203
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