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Chemokine Receptor CCR2b Enhanced Anti-tumor Function of Chimeric Antigen Receptor T Cells Targeting Mesothelin in a Non-small-cell Lung Carcinoma Model

Chimeric antigen receptor (CAR) T cell therapy faces a number of challenges for the treatment of non-small-cell lung carcinoma (NSCLC), and efficient migration of circulating CAR T cells plays an important role in anti-tumor activity. In this study, a CAR specific for tumor antigen mesothelin (Msln-...

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Detalles Bibliográficos
Autores principales:	Wang, Yanan, Wang, Jing, Yang, Xinyi, Yang, Jinlong, Lu, Panpan, Zhao, Lin, Li, Bokang, Pan, Hanyu, Jiang, Zhengtao, Shen, Xiaoting, Liang, Zhiming, Liang, Yue, Zhu, Huanzhang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992009/ https://www.ncbi.nlm.nih.gov/pubmed/33777013 http://dx.doi.org/10.3389/fimmu.2021.628906

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