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Feprazone Ameliorates TNF-α-Induced Loss of Aggrecan via Inhibition of the SOX-4/ADAMTS-5 Signaling Pathway

[Image: see text] Background: Arthritis is a cartilage degenerative disease that is mainly induced by the degradation of the cartilage extracellular matrix (ECM), which is found to be regulated by the expression level of a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMT-5), an...

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Detalles Bibliográficos
Autores principales: Xiong, Xiaoyang, Liu, Liang, Xu, Feng, Wu, Xiaofeng, Yin, Zifei, Dong, Yi, Qian, Pingkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992146/
https://www.ncbi.nlm.nih.gov/pubmed/33778274
http://dx.doi.org/10.1021/acsomega.0c06212

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