Cargando…

Schiff-Based Metal Complexes of Lamotrigine: Design, Synthesis, Characterization, and Biological Evaluation

[Image: see text] In the current study, a series of Schiff base derivatives of lamotrigine are complexed with zinc, copper, silver, and tin and characterized by spectroscopic techniques and biological assays. Docking analyses revealed six complexes with favorable binding interactions, which were fur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Najm, Saima, Naureen, Humaira, Sultana, Kishwar, Anwar, Fareeha, Khan, Muhammad Mubbashir, Nadeem, Humaira, Saeed, Muhammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992179/ https://www.ncbi.nlm.nih.gov/pubmed/33778282 http://dx.doi.org/10.1021/acsomega.1c00027

Ejemplares similares

Designing, synthesis and characterization of 2-aminothiazole-4-carboxylate Schiff bases; antimicrobial evaluation against multidrug resistant strains and molecular docking
por: Ejaz, Saima, et al.
Publicado: (2019)

Synthesis, Spectral Characterization, and Biological Evaluation of Transition Metal Complexes of Bidentate N, O Donor Schiff Bases
por: Sumrra, Sajjad Hussain, et al.
Publicado: (2014)

Schiff Bases of Pioglitazone Provide Better Antidiabetic and Potent Antioxidant Effect in a Streptozotocin–Nicotinamide-Induced Diabetic Rodent Model
por: Afzal, Hafiza Rabia, et al.
Publicado: (2021)

Glutathione sulfotransferase inhibition activity of a self-fermented beverage, Kanji
por: Latif, Abida, et al.
Publicado: (2016)

Design, synthesis and screening of indole acetic acid-based tri-azo moieties as antioxidants, anti-microbial and cytotoxic agents
por: Javaid, Maryam, et al.
Publicado: (2023)

Antibacterial Potential of Novel Acetamide Derivatives of 2-Mercaptobenzothiazole: Synthesis and Docking Studies
por: Sheikh, Ahmed Sadiq, et al.
Publicado: (2023)

Synthesis of Novel Bisindolylmethane Schiff bases and Their Antibacterial Activity
por: Imran, Syahrul, et al.
Publicado: (2014)

Synthesis, Biological Evaluation, 2D-QSAR, and Molecular Simulation Studies of Dihydropyrimidinone Derivatives as Alkaline Phosphatase Inhibitors
por: Altaf, Reem, et al.
Publicado: (2022)

Synthesis, DNA binding and biological evaluation of benzimidazole Schiff base ligands and their metal(ii) complexes
por: Mahmood, Khalid, et al.
Publicado: (2023)

Novel oxadiazole derivatives as potent inhibitors of α-amylase and α-glucosidase enzymes: Synthesis, in vitro evaluation, and molecular docking studies
por: Bukhari, Asma, et al.
Publicado: (2021)

Synthesis, Structural, and Biological Studies of Some Schiff Bases and Their Metal Complexes
por: Mishra, A. P., et al.
Publicado: (2008)

Synthesis, characterization, molecular docking and biological evaluation of Schiff Base derivatives of cefpodoxime
por: Mahmood, Waqas, et al.
Publicado: (2022)

Metal-Based Scaffolds of Schiff Bases Derived from Naproxen: Synthesis, Antibacterial Activities, and Molecular Docking Studies
por: Shaheen, Muhammad Ashraf, et al.
Publicado: (2019)

Biological synthesis of hybrid silver nanoparticles by Periploca aphylla Dcne. From nanotechnology to biotechnology applications
por: Arshad, Saba, et al.
Publicado: (2022)

Biological Regulatory Network (BRN) Analysis and Molecular Docking Simulations to Probe the Modulation of IP(3)R Mediated Ca(2+) Signaling in Cancer
por: Ismatullah, Humaira, et al.
Publicado: (2020)

Heavy Metal–Resistant Plant Growth–Promoting Citrobacter werkmanii Strain WWN1 and Enterobacter cloacae Strain JWM6 Enhance Wheat (Triticum aestivum L.) Growth by Modulating Physiological Attributes and Some Key Antioxidants Under Multi-Metal Stress
por: Ajmal, Abdul Wahab, et al.
Publicado: (2022)

Synthesis, biological evaluation and corrosion inhibition studies of transition metal complexes of Schiff base
por: Kashyap, Shubham, et al.
Publicado: (2018)

Prospective Application of Two New Pyridine-Based Zinc (II) Amide Carboxylate in Management of Alzheimer's Disease: Synthesis, Characterization, Computational and in vitro Approaches
por: Zafar, Rehman, et al.
Publicado: (2021)

Lamotrigine-Induced Acute Pancreatitis
por: Elmusa, Emad, et al.
Publicado: (2022)

EEG Based Classification of Long-Term Stress Using Psychological Labeling
por: Saeed, Sanay Muhammad Umar, et al.
Publicado: (2020)

Thermal Conductivity Enhancement of Metal Oxide Nanofluids: A Critical Review
por: Yasmin, Humaira, et al.
Publicado: (2023)

Genome wide meta-analysis of cDNA datasets reveals new target gene signatures of colorectal cancer based on systems biology approach
por: Ilyas, Umair, et al.
Publicado: (2020)

Correction to: Genome wide meta-analysis of cDNA datasets reveals new target gene signatures of colorectal cancer based on systems biology approach
por: Ilyas, Umair, et al.
Publicado: (2020)

Carvacrol derivatives as mushroom tyrosinase inhibitors; synthesis, kinetics mechanism and molecular docking studies
por: Ashraf, Zaman, et al.
Publicado: (2017)

Synthesis, solid state self-assembly driven by antiparallel π⋯π stacking and {⋯H–C–C–F}(2) dimer synthons, and in vitro acetyl cholinesterase inhibition activity of phenoxy pendant isatins
por: Mehreen, Saba, et al.
Publicado: (2022)

Novel Biologically Active N-Substituted Benzimidazole Derived Schiff Bases: Design, Synthesis, and Biological Evaluation
por: Beč, Anja, et al.
Publicado: (2023)

Lamotrigine-associated toxic epidermal necrolysis
por: Farooq, Omair, et al.
Publicado: (2023)

Synthesis and anti-nociceptive potential of isoxazole carboxamide derivatives
por: Bibi, Hajira, et al.
Publicado: (2019)

Synthesis, characterization, anti-ulcer action and molecular docking evaluation of novel benzimidazole-pyrazole hybrids
por: Noor, Abida, et al.
Publicado: (2017)

Design, Synthesis and Biological Evaluation of Some Triazole Schiff’s Base Derivatives as Potential Antitubercular Agents
por: Sager, Asma A., et al.
Publicado: (2018)

Rational use of antibiotics in an intensive care unit: a retrospective study of the impact on clinical outcomes and mortality rate
por: Ali, Muhammad, et al.
Publicado: (2019)

Renal Amyloidosis: A Clinicopathological Study From a Tertiary Care Hospital in Pakistan
por: Ahmed, Safina, et al.
Publicado: (2022)

Formation of morpholine-acetamide derivatives as potent anti-tumor drug candidates: Pharmacological evaluation and molecular docking studies
por: Sheikh, Ahmed Sadiq, et al.
Publicado: (2023)

Synthesis, characterization, molecular docking evaluation, antiplatelet and anticoagulant actions of 1,2,4 triazole hydrazone and sulphonamide novel derivatives
por: Khalid, Waseem, et al.
Publicado: (2018)

Synthesis and biological evaluation of Schiff bases and azetidinones of 1-naphthol
por: Kumar, Sushil, et al.
Publicado: (2012)

New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice
por: Kanwal, Madiha, et al.
Publicado: (2022)

Synthesis, Characterisation and Biological Activity of Thienoyl- and Furanoyl-Derived Schiff-Base Compounds With 3d Metal Ions
Publicado: (1998)

Pharmacotherapeutics of epilepsy: use of lamotrigine and expectations for lamotrigine extended release
por: Werz, Mary Ann
Publicado: (2008)

Synthesis, Characterization and Biocidal Activities of Some Schiff Base Metal Complexes
por: Neelakantan, M. A., et al.
Publicado: (2010)

Thiophene-Derived Schiff Base Complexes: Synthesis, Characterization, Antimicrobial Properties, and Molecular Docking
por: Nayab, Saira, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_q36md4tf274ofvo9i8k1tenj4t