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DDRE-22. TARGETING SERINE SYNTHESIS IN BRAIN METASTASIS

The brain environment is low in amino acids, including serine and glycine, both of which are important for tumor growth as they are precursors of proteins and nucleotide bases. How tumor cells overcome these conditions to proliferate and survive in the brain is incompletely understood. Here, we show...

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Detalles Bibliográficos
Autores principales: Ngo, Bryan, Kim, Eugenie, Osorio-Vasquez, Victoria, Doll, Sophia, Bustraan, Sophia, Liang, Roger, Luengo, Alba, Davidson, Shawn, Ali, Ahmed, Ferraro, Gino, Fischer, Grant, Plasger, Ariana, Rajasekhar, Vinagolu, Kastenhuber, Edward, Eskandari, Roozbeh, Bacha, Sarah, Sriram, Roshan, Bakhoum, Samuel, Snuderl, Matija, Cotzia, Paolo, Healey, John, Sabatini, David, Jones, Drew, Zhao, Jean, Yu, Min, Jain, Rakesh, Keshari, Kayvan, Davies, Michael, Heiden, Matthew Vander, Hernando, Eva, Mann, Matthias, Cantley, Lewis, Pacold, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992201/
http://dx.doi.org/10.1093/noajnl/vdab024.044

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