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DDRE-22. TARGETING SERINE SYNTHESIS IN BRAIN METASTASIS
The brain environment is low in amino acids, including serine and glycine, both of which are important for tumor growth as they are precursors of proteins and nucleotide bases. How tumor cells overcome these conditions to proliferate and survive in the brain is incompletely understood. Here, we show...
Autores principales: | Ngo, Bryan, Kim, Eugenie, Osorio-Vasquez, Victoria, Doll, Sophia, Bustraan, Sophia, Liang, Roger, Luengo, Alba, Davidson, Shawn, Ali, Ahmed, Ferraro, Gino, Fischer, Grant, Plasger, Ariana, Rajasekhar, Vinagolu, Kastenhuber, Edward, Eskandari, Roozbeh, Bacha, Sarah, Sriram, Roshan, Bakhoum, Samuel, Snuderl, Matija, Cotzia, Paolo, Healey, John, Sabatini, David, Jones, Drew, Zhao, Jean, Yu, Min, Jain, Rakesh, Keshari, Kayvan, Davies, Michael, Heiden, Matthew Vander, Hernando, Eva, Mann, Matthias, Cantley, Lewis, Pacold, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992201/ http://dx.doi.org/10.1093/noajnl/vdab024.044 |
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