DDRE-27. IDH MUTATED GLIOMAS PROMOTE EPILEPTOGENESIS VIA D-2-HYDROXYGLUTARATE DEPENDENT MTOR HYPERACTIVATION

INTRODUCTION: Epileptic seizures in patients with low-grade, isocitrate dehydrogenase (IDH) mutated gliomas reach 90%, a major source of morbidity for these patients. Albeit there are multiple features that contribute to tumor related epileptogenesis, IDH mutations are determined to be an independen...

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Detalles Bibliográficos
Autores principales: Mortazavi, Armin, Fayed, Islam, Bachani, Muzna, Dowdy, Tyrone, Steiner, Joseph, Maric, Dragan, Yang, Chun Zhang, Larion, Mioara, Ksendzovsky, Alexander, Zaghloul, Kareem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992218/
http://dx.doi.org/10.1093/noajnl/vdab024.049

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