DDRE-11. TARGETING FATTY ACID BIOSYNTHESIS IN GLIOBLASTOMA

We recently provided evidence that endoplasmic reticulum (ER) stress promotes fatty acid (FA) biosynthesis in glioblastoma (GBM) cancer stem cells (GSCs). We determined that Stearoyl CoA Desaturase 1 (SCD), a key FA desaturase, is essential for regulating ER homeostasis in GSCs, and showed that thes...

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Detalles Bibliográficos
Autores principales: Eyme, Katharina M, Neustadt, Rudolph, Badr, Christian E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992235/
http://dx.doi.org/10.1093/noajnl/vdab024.033

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