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FSMP-10. CYSTEINE INDUCES CYTOTOXICITY IN GLIOBLASTOMA THROUGH MITOCHONDRIAL HYDROGEN PEROXIDE PRODUCTION
Glioblastoma (GBM) is a poorly treatable disease with high mortality. Tumor metabolism in GBM is a critical mechanism responsible for growth because of upregulation of glucose, amino acid, and fatty acid utilization. However, little is known about the specific metabolic alterations in GBM that are t...
Autores principales: | Noch, Evan, Palma, Laura, Yim, Isaiah, Binder, Bhavneet, Benedetti, Elisa, Krumsiek, Jan, Elemento, Olivier, Cantley, Lewis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992237/ http://dx.doi.org/10.1093/noajnl/vdab024.074 |
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