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BIMG-05. TO BE OR NOT TO BE GLYCOLYTIC: DEUTERATED GLUCOSE-BASED ASSESSMENT OF THE WARBURG EFFECT ALLOWS NON-INVASIVE IMAGING OF TUMOR BURDEN AND TREATMENT RESPONSE IN MUTANT IDH GLIOMAS IN VIVO

The Warburg effect, characterized by elevated glucose uptake and flux to lactate, is a metabolic hallmark of cancer. Recent studies have identified deuterium (2)H-magnetic resonance spectroscopy (MRS) using 6,6’-(2)H-glucose as a novel method of imaging the Warburg effect in high-grade primary gliob...

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Detalles Bibliográficos
Autores principales: Taglang, Celine, Batsios, Georgios, Tran, Meryssa, Gillepsie, Anne Marie, Luchman, Hema Artee, Pieper, Russell O, Ronen, Sabrina M, Viswanath, Pavithra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992248/
http://dx.doi.org/10.1093/noajnl/vdab024.004