BIMG-07. PHARMACOLOGICAL ASCORBATE ENHANCES RADIATION AND TEMOZOLOMIDE EFFECTIVENESS IN GLIOBLASTOMA BY A MECHANISM MEDIATED BY REDOX ACTIVE IRON

Pharmacological ascorbate (P-AscH(-); high dose intravenous infusions of vitamin C generating milli-molar plasma concentrations) has re-emerged as an anti-cancer therapy. Phase 1 clinical trials combining P-AscH(-) with chemotherapy and ionizing radiation demonstrate safety and promising clinical ou...

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Detalles Bibliográficos
Autores principales: Allen, Bryan, Petronek, Michael, Monga, Varun, Bodeker, Kellie, Smith, Brian, Buettner, Garry, Greenlee, Jeremy, Smith, Mark, Spitz, Douglas, Cullen, Joseph, Magnotta, Vincent, Buatti, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992261/
http://dx.doi.org/10.1093/noajnl/vdab024.006

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