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DDRE-32. THERAPEUTIC TARGETING OF A NOVEL METABOLIC ADDICTION IN DIFFUSE MIDLINE GLIOMA

Diffuse midline glioma (DMG) is a uniformly fatal pediatric cancer that is in need of urgent “outside the box” therapeutic approaches. Recent studies show that tumor cells adapt to stresses created by oncogenic mutations and these oncogene-induced adaptations create vulnerabilities that can be explo...

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Detalles Bibliográficos
Autores principales: Pal, Sharmistha, Kaplan, Jakub P, Stopka, Sylwia A, Regan, Michael S, Hunsel, Bradley R, Kann, Benjamin H, Agar, Nathalie Y R, Stiles, Charles D, Cooney, Tabitha M, Mueller, Sabine, Chowdhury, Dipanjan, Kaelin, William G, McBrayer, Samuel K, Haas-Kogan, Daphne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992269/
http://dx.doi.org/10.1093/noajnl/vdab024.054