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DDRE-18. THE MITOCHONDRIAL PYRUVATE CARRIER—A METABOLIC TARGET OF MALIGNANT GLIOMA

Metabolic reprogramming has been recognized as crucial to the survival and proliferation of cancer cells through the reduction of glucose oxidation (the Warburg effect) and diversion of pyruvate and glycolytic metabolites to fuel anabolic processes. The mitochondrial pyruvate carrier (MPC) protein c...

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Detalles Bibliográficos
Autores principales: Tiburcio, Patricia, Murnyak, Balazs, Coffman, Kimberly, Huang, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992274/
http://dx.doi.org/10.1093/noajnl/vdab024.040

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