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Detection of tumor-derived extracellular vesicles in plasma from patients with solid cancer
BACKGROUND: Extracellular vesicles (EVs) are actively secreted by cells into body fluids and contain nucleic acids of the cells they originate from. The goal of this study was to detect circulating tumor-derived EVs (ctEVs) by mutant mRNA transcripts (EV-RNA) in plasma of patients with solid cancers...
Autores principales: | Vitale, Silvia R., Helmijr, Jean A., Gerritsen, Marjolein, Coban, Hicret, van Dessel, Lisanne F., Beije, Nick, van der Vlugt-Daane, Michelle, Vigneri, Paolo, Sieuwerts, Anieta M., Dits, Natasja, van Royen, Martin E., Jenster, Guido, Sleijfer, Stefan, Lolkema, Martijn, Martens, John W. M., Jansen, Maurice P. H. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992353/ https://www.ncbi.nlm.nih.gov/pubmed/33761899 http://dx.doi.org/10.1186/s12885-021-08007-z |
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