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A Case of Solitary Fibrous Tumor of Subungual Region

Solitary fibrous tumor (SFT) is a relatively uncommon mesenchymal neoplasm that usually arises in the pleura, but also has been reported in numerous extrapleural locations, including cutaneous site. The skin lesion presents as a circumscribed nodule or tumor, mainly on the head and neck. A 41-year-o...

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Autores principales: An, Min Kyun, Hong, Eun Hye, Cho, Eun Byul, Park, Eun Joo, Kim, Kwang Ho, Kim, Kwang Joong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992551/
https://www.ncbi.nlm.nih.gov/pubmed/33911726
http://dx.doi.org/10.5021/ad.2020.32.2.146
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author An, Min Kyun
Hong, Eun Hye
Cho, Eun Byul
Park, Eun Joo
Kim, Kwang Ho
Kim, Kwang Joong
author_facet An, Min Kyun
Hong, Eun Hye
Cho, Eun Byul
Park, Eun Joo
Kim, Kwang Ho
Kim, Kwang Joong
author_sort An, Min Kyun
collection PubMed
description Solitary fibrous tumor (SFT) is a relatively uncommon mesenchymal neoplasm that usually arises in the pleura, but also has been reported in numerous extrapleural locations, including cutaneous site. The skin lesion presents as a circumscribed nodule or tumor, mainly on the head and neck. A 41-year-old male presented with 6 months history of nail lesion without symptom on the left third finger. The lesion is slightly yellowish discoloration with subungual erythematous nodule and distal onycholysis. Biopsy specimen from the nail lesion showed the spindle cells form patternless pattern with hypercellular and hypocellular area. And small blood vessels and dilated vascular spaces were present. The result of special stain for specimen showed that positive for CD34, Bcl-2, and CD99 but negative for S-100, FactorXIIIa, and smooth muscle action. Recognition of this uncommon location of SFT is important because of possible confusion with other subungual tumors, including glomus tumor, fibroma and other fibrohistiocytic tumors like dermatofibrosarcoma protuberans, superficial acral fibromyxoma and cellular digital fibroma. Here in, we report a case of SFT of subungual region. We think this case is interesting because of uncommon location and may be helpful to more understand the character of this disease.
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spelling pubmed-79925512021-04-27 A Case of Solitary Fibrous Tumor of Subungual Region An, Min Kyun Hong, Eun Hye Cho, Eun Byul Park, Eun Joo Kim, Kwang Ho Kim, Kwang Joong Ann Dermatol Case Report Solitary fibrous tumor (SFT) is a relatively uncommon mesenchymal neoplasm that usually arises in the pleura, but also has been reported in numerous extrapleural locations, including cutaneous site. The skin lesion presents as a circumscribed nodule or tumor, mainly on the head and neck. A 41-year-old male presented with 6 months history of nail lesion without symptom on the left third finger. The lesion is slightly yellowish discoloration with subungual erythematous nodule and distal onycholysis. Biopsy specimen from the nail lesion showed the spindle cells form patternless pattern with hypercellular and hypocellular area. And small blood vessels and dilated vascular spaces were present. The result of special stain for specimen showed that positive for CD34, Bcl-2, and CD99 but negative for S-100, FactorXIIIa, and smooth muscle action. Recognition of this uncommon location of SFT is important because of possible confusion with other subungual tumors, including glomus tumor, fibroma and other fibrohistiocytic tumors like dermatofibrosarcoma protuberans, superficial acral fibromyxoma and cellular digital fibroma. Here in, we report a case of SFT of subungual region. We think this case is interesting because of uncommon location and may be helpful to more understand the character of this disease. The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2020-04 2020-03-11 /pmc/articles/PMC7992551/ /pubmed/33911726 http://dx.doi.org/10.5021/ad.2020.32.2.146 Text en Copyright © 2020 The Korean Dermatological Association and The Korean Society for Investigative Dermatology http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
An, Min Kyun
Hong, Eun Hye
Cho, Eun Byul
Park, Eun Joo
Kim, Kwang Ho
Kim, Kwang Joong
A Case of Solitary Fibrous Tumor of Subungual Region
title A Case of Solitary Fibrous Tumor of Subungual Region
title_full A Case of Solitary Fibrous Tumor of Subungual Region
title_fullStr A Case of Solitary Fibrous Tumor of Subungual Region
title_full_unstemmed A Case of Solitary Fibrous Tumor of Subungual Region
title_short A Case of Solitary Fibrous Tumor of Subungual Region
title_sort case of solitary fibrous tumor of subungual region
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992551/
https://www.ncbi.nlm.nih.gov/pubmed/33911726
http://dx.doi.org/10.5021/ad.2020.32.2.146
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