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A Report of 13 Cases of Merkel Cell Carcinoma: Single-Center Experience and Review of the Literature

BACKGROUND: There is limited data knowledge of Merkel cell carcinoma (MCC) in Turkey aside from a few case reports. OBJECTIVE: The aim of this study was to describe the clinical characteristics, demographic features, therapeutic parameters, and outcome of primary cutaneous MCC cases from Turkey. MET...

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Autores principales: Yazici, Serkan, Irmak Yazici, Elif, Balaban Adim, Saduman, Bulbul Baskan, Emel, Aydoğan, Kenan, Saricaoğlu, Hayriye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992734/
https://www.ncbi.nlm.nih.gov/pubmed/33911591
http://dx.doi.org/10.5021/ad.2019.31.3.272
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author Yazici, Serkan
Irmak Yazici, Elif
Balaban Adim, Saduman
Bulbul Baskan, Emel
Aydoğan, Kenan
Saricaoğlu, Hayriye
author_facet Yazici, Serkan
Irmak Yazici, Elif
Balaban Adim, Saduman
Bulbul Baskan, Emel
Aydoğan, Kenan
Saricaoğlu, Hayriye
author_sort Yazici, Serkan
collection PubMed
description BACKGROUND: There is limited data knowledge of Merkel cell carcinoma (MCC) in Turkey aside from a few case reports. OBJECTIVE: The aim of this study was to describe the clinical characteristics, demographic features, therapeutic parameters, and outcome of primary cutaneous MCC cases from Turkey. METHODS: Digital medical records of the 13 MCC patients who were followed-up at a tertiary referral center were retrospectively analyzed. Clinic, demographic, tumor characteristics, and survival of the patients were retrieved. RESULTS: Most of our patients were elderly. Female predominance was noticed. The most common primary site of the tumors was the lower extremities. The overall survival was 42 months, 68% at first year, 68% at third years, and 29% at fifth years. CONCLUSION: This is the first largest report from Turkish population with female predominance, and lower extremity tendency.
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spelling pubmed-79927342021-04-27 A Report of 13 Cases of Merkel Cell Carcinoma: Single-Center Experience and Review of the Literature Yazici, Serkan Irmak Yazici, Elif Balaban Adim, Saduman Bulbul Baskan, Emel Aydoğan, Kenan Saricaoğlu, Hayriye Ann Dermatol Original Article BACKGROUND: There is limited data knowledge of Merkel cell carcinoma (MCC) in Turkey aside from a few case reports. OBJECTIVE: The aim of this study was to describe the clinical characteristics, demographic features, therapeutic parameters, and outcome of primary cutaneous MCC cases from Turkey. METHODS: Digital medical records of the 13 MCC patients who were followed-up at a tertiary referral center were retrospectively analyzed. Clinic, demographic, tumor characteristics, and survival of the patients were retrieved. RESULTS: Most of our patients were elderly. Female predominance was noticed. The most common primary site of the tumors was the lower extremities. The overall survival was 42 months, 68% at first year, 68% at third years, and 29% at fifth years. CONCLUSION: This is the first largest report from Turkish population with female predominance, and lower extremity tendency. The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2019-06 2019-05-01 /pmc/articles/PMC7992734/ /pubmed/33911591 http://dx.doi.org/10.5021/ad.2019.31.3.272 Text en Copyright © 2019 The Korean Dermatological Association and The Korean Society for Investigative Dermatology http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Yazici, Serkan
Irmak Yazici, Elif
Balaban Adim, Saduman
Bulbul Baskan, Emel
Aydoğan, Kenan
Saricaoğlu, Hayriye
A Report of 13 Cases of Merkel Cell Carcinoma: Single-Center Experience and Review of the Literature
title A Report of 13 Cases of Merkel Cell Carcinoma: Single-Center Experience and Review of the Literature
title_full A Report of 13 Cases of Merkel Cell Carcinoma: Single-Center Experience and Review of the Literature
title_fullStr A Report of 13 Cases of Merkel Cell Carcinoma: Single-Center Experience and Review of the Literature
title_full_unstemmed A Report of 13 Cases of Merkel Cell Carcinoma: Single-Center Experience and Review of the Literature
title_short A Report of 13 Cases of Merkel Cell Carcinoma: Single-Center Experience and Review of the Literature
title_sort report of 13 cases of merkel cell carcinoma: single-center experience and review of the literature
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992734/
https://www.ncbi.nlm.nih.gov/pubmed/33911591
http://dx.doi.org/10.5021/ad.2019.31.3.272
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