Cargando…
CDKN2A germline alterations and the relevance of genotype-phenotype associations in cancer predisposition
Although CDKN2A is well-known as a susceptibility gene for melanoma and pancreatic cancer, germline variants have also been anecdotally associated with a broader range of neoplasms including neural system tumors, head and neck squamous cell carcinomas, breast carcinomas, as well as sarcomas. The CDK...
Autores principales: | Chan, Sock Hoai, Chiang, Jianbang, Ngeow, Joanne |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992806/ https://www.ncbi.nlm.nih.gov/pubmed/33766116 http://dx.doi.org/10.1186/s13053-021-00178-x |
Ejemplares similares
-
Understanding cancer predisposition in Singapore: what's next
por: Chiang, Jianbang, et al.
Publicado: (2023) -
COVID-19 vaccination uptake and safety profile among germline BRCA1 and BRCA2 pathogenic variant carriers in Singapore
por: Zhang, Zewen, et al.
Publicado: (2023) -
Case report: olaparib use in metastatic lung adenocarcinoma with BRCA2 pathogenic variant
por: Soon Jian Hao, Jonathan, et al.
Publicado: (2022) -
Germline Mutations in Cancer Predisposition Genes are Frequent in Sporadic Sarcomas
por: Chan, Sock Hoai, et al.
Publicado: (2017) -
Germline hemizygous deletion of CDKN2A–CDKN2B locus in a patient presenting with Li–Fraumeni syndrome
por: Chan, Sock Hoai, et al.
Publicado: (2016)