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Therapies with CCL25 require controlled release via microparticles to avoid strong inflammatory reactions
BACKGROUND: Chemokine therapy with C–C motif chemokine ligand 25 (CCL25) is currently under investigation as a promising approach to treat articular cartilage degeneration. We developed a delayed release mechanism based on Poly (lactic-co-glycolic acid) (PLGA) microparticle encapsulation for intraar...
Autores principales: | Spinnen, J., Fröhlich, K., Sinner, N., Stolk, M., Ringe, J., Shopperly, L., Sittinger, M., Dehne, T., Seifert, M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992824/ https://www.ncbi.nlm.nih.gov/pubmed/33766057 http://dx.doi.org/10.1186/s12951-021-00830-7 |
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