Discovery of LAMP-2A as potential biomarkers for glioblastoma development by modulating apoptosis through N-CoR degradation

BACKGROUND: Lysosome-associated membrane protein type 2A (LAMP-2A) is the key component of chaperone-mediated autophagy (CMA), a cargo-selective lysosomal degradation pathway. Aberrant LAMP-2A expression and CMA activation have been demonstrated in various human malignancies. The study focusing on t...

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Detalles Bibliográficos
Autores principales: Wang, Yongjie, Zhang, Buyi, Wang, Jianli, Wu, Haijian, Xu, Shenbin, Zhang, Jianmin, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992845/
https://www.ncbi.nlm.nih.gov/pubmed/33761934
http://dx.doi.org/10.1186/s12964-021-00729-8

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