Genome-wide impact of hydrogen peroxide on maintenance DNA methylation in replicating cells

BACKGROUND: Environmental factors, such as oxidative stress, have the potential to modify the epigenetic landscape of cells. We have previously shown that DNA methyltransferase (DNMT) activity can be inhibited by sublethal doses of hydrogen peroxide (H(2)O(2)). However, site-specific changes in DNA...

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Detalles Bibliográficos
Autores principales: Seddon, Annika R., Liau, Yusmiati, Pace, Paul E., Miller, Allison L., Das, Andrew B., Kennedy, Martin A., Hampton, Mark B., Stevens, Aaron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992848/
https://www.ncbi.nlm.nih.gov/pubmed/33761969
http://dx.doi.org/10.1186/s13072-021-00388-6

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