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Attenuated TGFB signalling in macrophages decreases susceptibility to DMBA-induced mammary cancer in mice

BACKGROUND: Transforming growth factor beta1 (TGFB1) is a multi-functional cytokine that regulates mammary gland development and cancer progression through endocrine, paracrine and autocrine mechanisms. TGFB1 also plays roles in tumour development and progression, and its increased expression is ass...

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Detalles Bibliográficos
Autores principales:	Sun, Xuan, Bernhardt, Sarah M., Glynn, Danielle J., Hodson, Leigh J., Woolford, Lucy, Evdokiou, Andreas, Yan, Cong, Du, Hong, Robertson, Sarah A., Ingman, Wendy V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992865/ https://www.ncbi.nlm.nih.gov/pubmed/33761981 http://dx.doi.org/10.1186/s13058-021-01417-8

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