Cargando…
Finding an easy way to harmonize: a review of advances in clinical research and combination strategies of EZH2 inhibitors
Enhancer of zeste homolog 2 inhibitors (EZH2i) have garnered increased attention owing to their anticancer activity by targeting EZH2, a well-known cancer-promoting factor. However, some lymphomas are resistant to EZH2i, and EZH2i treatment alone is ineffective in case of EZH2-overexpressing solid t...
Autores principales: | Li, Chen, Wang, Yan, Gong, Yueqing, Zhang, Tengrui, Huang, Jiaqi, Tan, Zhen, Xue, Lixiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992945/ https://www.ncbi.nlm.nih.gov/pubmed/33761979 http://dx.doi.org/10.1186/s13148-021-01045-1 |
Ejemplares similares
-
Symphony of epigenetic and metabolic regulation—interaction between the histone methyltransferase EZH2 and metabolism of tumor
por: Zhang, Tengrui, et al.
Publicado: (2020) -
Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor
por: Zhang, Tengrui, et al.
Publicado: (2022) -
Easy or Not—The Advances of EZH2 in Regulating T Cell Development, Differentiation, and Activation in Antitumor Immunity
por: Huang, Jiaqi, et al.
Publicado: (2021) -
EZH2 Inhibitors Suppress Colorectal Cancer by Regulating Macrophage Polarization in the Tumor Microenvironment
por: Li, Chen, et al.
Publicado: (2022) -
No Easy Way Out for EZH2: Its Pleiotropic, Noncanonical Effects on Gene Regulation and Cellular Function
por: Wang, Jun, et al.
Publicado: (2020)