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Polymicrobial Pseudomonas Plus Candida Parapsilosis Endocarditis in an Injection Drug User: Considerations for Diagnosis and Management

Fungal endocarditis (FE) is a potentially lethal condition and its diagnosis can be challenging due to the low yield from blood cultures. FE should be suspected in patients with associated risk factors despite the identification of positive bacterial blood cultures. The common risk factors for FE di...

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Autores principales: Kaur, Maninder, Virdi, Parminder, Kaur, Ramanjit, Abidov, Aiden, Levine, Diane L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993063/
https://www.ncbi.nlm.nih.gov/pubmed/33786216
http://dx.doi.org/10.7759/cureus.13507
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author Kaur, Maninder
Virdi, Parminder
Kaur, Ramanjit
Abidov, Aiden
Levine, Diane L
author_facet Kaur, Maninder
Virdi, Parminder
Kaur, Ramanjit
Abidov, Aiden
Levine, Diane L
author_sort Kaur, Maninder
collection PubMed
description Fungal endocarditis (FE) is a potentially lethal condition and its diagnosis can be challenging due to the low yield from blood cultures. FE should be suspected in patients with associated risk factors despite the identification of positive bacterial blood cultures. The common risk factors for FE discussed in the literature are total parenteral nutrition, immune suppression, prior antimicrobial therapy, intravenous drug addiction, and cardiac surgery. In this report, we discuss a patient who had positive blood cultures for Pseudomonas but was found to have Candida parapsilosis on valve culture. Physicians need to maintain a high index of suspicion for co-infective endocarditis in this patient population.
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spelling pubmed-79930632021-03-29 Polymicrobial Pseudomonas Plus Candida Parapsilosis Endocarditis in an Injection Drug User: Considerations for Diagnosis and Management Kaur, Maninder Virdi, Parminder Kaur, Ramanjit Abidov, Aiden Levine, Diane L Cureus Internal Medicine Fungal endocarditis (FE) is a potentially lethal condition and its diagnosis can be challenging due to the low yield from blood cultures. FE should be suspected in patients with associated risk factors despite the identification of positive bacterial blood cultures. The common risk factors for FE discussed in the literature are total parenteral nutrition, immune suppression, prior antimicrobial therapy, intravenous drug addiction, and cardiac surgery. In this report, we discuss a patient who had positive blood cultures for Pseudomonas but was found to have Candida parapsilosis on valve culture. Physicians need to maintain a high index of suspicion for co-infective endocarditis in this patient population. Cureus 2021-02-23 /pmc/articles/PMC7993063/ /pubmed/33786216 http://dx.doi.org/10.7759/cureus.13507 Text en Copyright © 2021, Kaur et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Kaur, Maninder
Virdi, Parminder
Kaur, Ramanjit
Abidov, Aiden
Levine, Diane L
Polymicrobial Pseudomonas Plus Candida Parapsilosis Endocarditis in an Injection Drug User: Considerations for Diagnosis and Management
title Polymicrobial Pseudomonas Plus Candida Parapsilosis Endocarditis in an Injection Drug User: Considerations for Diagnosis and Management
title_full Polymicrobial Pseudomonas Plus Candida Parapsilosis Endocarditis in an Injection Drug User: Considerations for Diagnosis and Management
title_fullStr Polymicrobial Pseudomonas Plus Candida Parapsilosis Endocarditis in an Injection Drug User: Considerations for Diagnosis and Management
title_full_unstemmed Polymicrobial Pseudomonas Plus Candida Parapsilosis Endocarditis in an Injection Drug User: Considerations for Diagnosis and Management
title_short Polymicrobial Pseudomonas Plus Candida Parapsilosis Endocarditis in an Injection Drug User: Considerations for Diagnosis and Management
title_sort polymicrobial pseudomonas plus candida parapsilosis endocarditis in an injection drug user: considerations for diagnosis and management
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993063/
https://www.ncbi.nlm.nih.gov/pubmed/33786216
http://dx.doi.org/10.7759/cureus.13507
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