Reactive Oxygen Species Rewires Metabolic Activity in Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a heterogeneous disease with poor clinical outcomes. We have previously shown that constitutive activation of NADPH oxidase 2 (NOX2), resulting in over-production of reactive oxygen species (ROS), occurs in over 60% of AML patients. We have also shown that increased R...

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Detalles Bibliográficos
Autores principales: Robinson, Andrew J., Davies, Sara, Darley, Richard L., Tonks, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993200/
https://www.ncbi.nlm.nih.gov/pubmed/33777786
http://dx.doi.org/10.3389/fonc.2021.632623

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