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Immunogenicity risk assessment for biotherapeutics through in vitro detection of CD134 and CD137 on T helper cells
Biotherapeutics, which are biologic medications that are natural or bioengineered products of living cells, have revolutionized the treatment of many diseases. However, unwanted immune responses still present a major challenge to their widespread adoption. Many patients treated with biotherapeutics...
Autores principales: | Cohen, Sivan, Myneni, Srividya, Batt, Anna, Guerrero, Joyce, Brumm, Jochen, Chung, Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993230/ https://www.ncbi.nlm.nih.gov/pubmed/33729092 http://dx.doi.org/10.1080/19420862.2021.1898831 |
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