Effect of Crohn’s Disease on Villous Length and CYP3A4 Expression in the Pediatric Small Intestine

Changes in absorptive capacity and first‐pass metabolism in the small intestine affect oral drug bioavailability. Characterization of such changes as a consequence of inflammation is important for developing physiologically‐based pharmacokinetic (PBPK) models for inflammatory bowel disease. We sough...

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Detalles Bibliográficos
Autores principales: Vyhlidal, Carrie A, Chapron, Brian D., Ahmed, Atif, Singh, Vivekanand, Casini, Rebecca, Shakhnovich, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993283/
https://www.ncbi.nlm.nih.gov/pubmed/33278326
http://dx.doi.org/10.1111/cts.12938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993283/
https://www.ncbi.nlm.nih.gov/pubmed/33278326
http://dx.doi.org/10.1111/cts.12938

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